results hpv-16 e6 and e7 proteins reduced e-cadherin expression 3.7 and 2.2 times when compared with control cells (p = 0.0221 and p = 0.0461, respectively). this reduction was greater in hpv-16 e6-expressing cells than in hpv-16 e7-expressing cells. although hpv-16 e6 and e7 increased dna methyltransferase 1 expression 2.6 and 3.4 times, respectively (p = 0.0133 and p = 0.0113) when compared w...

background: e-cadherin is a calcium-dependent molecule that contributes to intercellular adhesion. its proper functioning is important in the maintenance of epithelial structure and integrity. e-cadherin serves as a very important tumor suppressor. in this study, we aimâ to determineâ the frequencyâ of e-cadherin expression aberrancy and its relationship to theâ biologicalâ behavior of gastric ...

abstract background: gastric cancer is one of the most common cancers in the world especially in iran. there are many genomic and molecular factors that cause gastric cancer to occur. also, many markers that associate with tumor invasiveness have been known.  e-cadherin is a calcium- mediated cell adhesion molecule. in some studies, abnormal expression of e-cadherin has been seen in gastric car...

conclusions abnormal e-cadherin expression is a common phenomenon in gastric adenocarcinoma. the study showed a significant correlation between abnormal e-cadherin expression and tumor grade and regional lymph node involvement; so, abnormal e-cadherin expression may be used as a predictive factor for tumor invasiveness in gastric adenocarcinoma. materials and methods a historical cohort survey ...

objective: e-cadherin is a classic cadherin that plays a key role in epithelial cell adhesion. this protein is being referred to as the suppressor of proliferation and invasion. limited studies have investigated e-cadherin expression in salivary gland neoplasms. this study sought to assess the expression of e-cadherin and its possible role in progression and invasion of salivary gland neoplasms...