BACKGROUND The biologically active component of a hormone is the unbound or free fraction. Changes in cortisol-binding protein could give misleading results if only total cortisol is measured for the interpretation of dynamic function tests. METHODS This study aimed to measure serum free cortisol using a steady-state gel-filtration method and then to evaluate the correlation between the serum...

ABSTRACT              Background and Objectives: Cancer and its conventional treatments may bring about some psychological and health-related symptoms leading to unstable cortisol level. Since evidence has shown that mindfulness based approaches can be helpful to reduce cortisol level, we aimed at investigating the efficacy of &n...

anxiety is one of the prevalent mental health disorders. stressors by changes in physiology can increase risk of physical diseases. high levels of cortisol have many negative effects on health. this study aimed to determine anxiety symptoms prevalence and its relationships with plasma cortisol level. this study was a descriptive- analytical cross-sectional that was conducted on 100 nursing stud...

BACKGROUND Levels of cortisol, the end product of the hypothalamic-pituitary-adrenal (HPA) axis, display a sharp increase immediately upon awakening, known as the cortisol awakening response (CAR). The daily stability of the CAR is potentially influenced by a range of methodological factors, including light exposure, participant adherence, sleep duration and nocturnal awakenings, making inferen...

Anxiety is one of the prevalent mental health disorders. Stressors by changes in physiology can increase risk of physical diseases. High levels of cortisol have many negative effects on health. This study aimed to determine Anxiety symptoms prevalence and its relationships with plasma cortisol level. This study was a descriptive- analytical cross-sectional that was conducted on 100 nursing stud...

background: malignancy and its treatments could cause disturbance in homeostasis of body such as cortisol secretion. the present study has investigated the effects of cortisol level imbalance in behavioral and emotional adjustments. methods: seventy-eight children with acute lymphoblastic leukemia (all) have involved in this study. their salivary cortisol level, which were sensitive to pain and...

recognized as a reliable tool for assessing the hypothalamus-pituitary-adrenal (hpa) axis, measurement of salivary cortisol plays an important role in both the clinical and research settings. to establish a normative data, which forms the basis for the usage of this valuable parameter, we gathered 8:00 h saliva samples from 94 healthy individuals aged 6-14 years. cortisol levels were measured b...