In this paper, the usage of graphene transistors is introduced to be a suitable solution for extending low power designs. Static and current mode logic (CML) styles on both nanoscale silicon FINFET technologies are compared. Results show that in CML approximately independent frequency graphene-based (G-CML) designs more power-efficient as complexity increase. Compared silicon-based (Si-CML) sta...

Tyrosine kinase inhibitors (TKIs) are the mainstay of current management chronic myeloid leukemia (CML) [1]. With introduction imatinib, many CML patients in phase (CML-CP) we...

background the induction ofâ  cancers incidence by exogenous agents, such as chemical, radiation and especially research on viruses is an interestedâ  area of active basic subjectsâ  and clinical investigation. prominent researches sounds aâ  high prevalence of hbv marker has been found in patients with leukemia as compared to the general population. methods: presentâ  â study was conducted fro...

Objective(s): Chronic myelogenous leukemia (CML) is a chronic myeloproliferative disorder characterized by the accumulation of myeloid cells with a chromosomal translocation known as the Philadelphia chromosome. In this study, we investigated the roles of miR-570 in CML development. Materials and Methods: Expression of miR-570 in CML samples and cell lines was determined by qRT-PCR. Glucose upt...

Chronic myeloid leukemia (CML) is caused by the reciprocal translocation t(9;22)(q34;q11), resulting in BCR-ABL1 fusion gene. tyrosine kinase inhibitors (TKIs) improve overall survival patients with chronic phase CML (CML-CP). Approximately half of who achieve a durable deep molecular response can sustained treatment-free remission (TFR) after TKI discontinuation; thus TFR now therapeutic goal ...

Background: Solid tumors may occur in 3% of the patients with chronic myeloid leukemia (CML). In this paper, we presented a case of CML following treatment of colon cancer. Case Presentation: A 25 year old man was diagnosed of adenocarcinoma of rectosigmoid treated with fluorouracil-based chemotherapy. Following relapse, he received florouracil, oxaliplatin and irinotecan during the next year. ...

Chronic myeloid leukemia (CML) is a myeloproliferative disorder that caused by the formation of fusion onco-protein, BCR-ABL. Since BCR-ABL plays role in progression CML, most common treatments CML are tyrosine kinase inhibitors (TKIs) specifically target However, resistance to TKIs major problem treatment. A promising overcoming drug other cancers thioredoxin (TRX) system, an antioxidant syste...