www.thelancet.com Vol 384 October 11, 2014 1345 as 1–2% chlorhexidine in isopropyl alcohol, but we agree with Maiwald and colleagues that adequate studies to support or reject this hypothesis have not yet been done. Chlorhexidine in an alcoholic solution, however, is clearly superior to povidone-iodine for prevention of vascular catheter-related bloodstream infec tion. Maiwald and colleagues ha...

This study successfully developed a positively charged silver nanocomplex as nanocarrier for chlorhexidine (CHX) using ionic liquids. can interestingly deliver the antibacterial agent with synergistic effect. In this study, we synthetized and characterized (AgNPs+) CHX-loaded nanoparticles (CHX@AgNPs+) UV-visible spectroscopy, transmission electron microscopy, X-ray diffractometer, Fourier tran...

OBJECTIVES To investigate the development of post-extraction bacteraemia (PEB) after the prophylactic use of chlorhexidine (CHX). PATIENTS AND METHODS A total of 201 patients who underwent a tooth extraction were randomly distributed into four groups: 52 received no prophylaxis (CONTROL), 50 did a mouthwash with 0.2% CHX before the tooth extraction (CHX-MW), 51 did a mouthwash with 0.2% CHX a...

Objective.Chlorhexidine gluconate (CHX) is an irrigant with a  reasonable antibacterial ability and rather high permeability yet often fails to remove the smear layer. To solve this problem, CHX is upgraded through its complexion with chitosan (CS). Methods.Molar roots are split longitudinally by a rotary diamond saw. Chlorhexidine-chitosan (CHX-CS) is made by combinatio...

RATIONALE Ventilator-associated pneumonia (VAP) is the most frequently occurring nosocomial infection associated with increased morbidity and mortality. Although oral decontamination with antibiotics reduces incidences of VAP, it is not recommended because of potential selection of antibiotic-resistant pathogens. We hypothesized that oral decontamination with either chlorhexidine (CHX, 2%) or C...

Results 10 primary studies were grouped in 4 groups (G1-4) based in criteria of concentration of CHX. G1 (10 primary studies with different concentrations of CHX) studies were homogeneous (Cochrane Q het p=0.35) and the common RR was significative (p<0.001 and CI=95%); G2 (5 primary studies CHX 0.12%) showed homogeneity (Cochrane Q het p=0.67) and the use of CHX represented protection (p<0.05);...

Albert [1] GSE55400 BY FP Artieri [2] GSE50049 non multiplexed Artieri [3] SRP033885 Mixed parental ribosome protected fragments replicate 1 Brar [4] GSE34082 footprints for exponential vegetative cells of the strain gb15 used for the traditional timecourse Dunn [5] obtained from authors only one sample Gardin [6] GSE51164 ribosome footprints for wildtype Gerashchenko (NAR) [7] GSE59573 many sa...

BACKGROUND A strong antimicrobial synergism between chlorhexidine (CHX) and hydrogen peroxide (H2O2) has been reported, but there is not enough data on the cytotoxicity of this combination. The primary aim of this study was to evaluate the cytotoxicity of CHX-H2O2 combination in different concentrations and secondary aim is to assess the influence of H2O2 on cytotoxicity of CHX on cultured huma...

Abstract Background A low pH environment is created due to the production of acids by oral biofilms that further leads dissolution hydroxyapatite crystal in tooth structure significantly altering equilibrium. Although overall bacterial counts may not be eradicated from cavity, however, synthesis engineered anti-bacterial materials are warranted reduce pathogenic impact biofilms. The purpose thi...