Background: Documents constructed according to the HL7 Clinical Document Architecture (CDA) need to be reviewed, edited and approved by an author, who is usually a clinician. The CDA specification does not require any particular editing tool to be used in creating CDAs. The tools used to edit CDAs have typically been specific to a particular profile of CDA, and even to the application using tha...

BACKGROUND Cervical disc arthroplasty (CDA) is a novel motion-preserving procedure that is an alternative to fusion. The Mobi-C disc prosthesis, one of many Food and Drug Administration (FDA)-approved devices for CDA, is the only FDA-approved prosthesis for two-level CDA. Hence, it may allow for improved outcomes compared with multilevel fusion procedures. PURPOSE To critically assess the ava...

The agent 2-chlorodeoxyadenosine (2-CdA) has chemotherapeutic activity in hairy cell leukemia (HCL) and in refractory chronic lymphocytic leukemia (CLL). The cytotoxic activity of 2-CdA requires the intracellular accumulation of 2-CdA nucleotides. Deoxycytidine kinase (dCK) and cytoplasmic 5'-nucleotidase (5'-NT) are the principal enzymes that phosphorylate 2-CdA and dephosphorylate 2-CdA 5'-mo...

A Continuous Double Auction (CDA) is a powerful auction mechanism used in online share trading. A CDA has many buyers and sellers continually exchanging items. Implementing an online CDA in software is more complicated than a regular online auction (such as eBay). This paper describes our experiences with implementing an online CDA. We present the model as an abstraction of the online share tra...

Since 1995, BAE Systems Electronics, Intelligence & Support (EI&S) has been developing and demonstrating the Commander‘s Decision Aid (CDA), a generalized sensor/information fusion processor and resource/response manager for integrated defense of ground combat vehicles. The CDA was developed under several contracts to Prime Contractor United Defense for the U.S. Army Tankautomotive & Armaments ...

Langmuir–Blodgett (LB) technique has been used to deposit composite multilayers of poly (3-octylthiophene)-cadmium arachidate (POT-CdA) and polyaniline-cadmium arachidate (PANI-CdA). These were used as precursors to develop semiconducting CdS nanoclusters within the conducting polymer based multilayers. The presence of CdS in the multilayers was determined by Fourier transform infrared spectros...

Cytidine deaminase (CDA) purified from human placenta revealed the presence of five isoenzymatic forms that differ only in their isoelectric point. Since human cytidine deaminase exists in two variants (CDA 1 and CDA 2) with a non-conservative amino acid substitution at codon 27, in this work we demonstrate that these two variants may combine together in vitro, giving five CDA isoforms as obser...

2-Chloro-2'-deoxyadenosine (CdA; cladribine) is a chemotherapeutic agent used in the treatment of certain leukemias. However, the signalling events that govern CdA-mediated cytotoxicity in leukemia cells remain unclear. We show here that CdA treatment caused Jurkat human T leukemia cells to die via apoptosis in a dose- and time-dependent fashion. Bcl-2 overexpression protected Jurkat T leukemia...

Clinical Document Architecture (CDA) is a standard for the exchange of electronic medical records. This paper describes a self-protecting security framework for protecting the security and privacy of CDA documents. The framework extends a CDA document with markups from XML based security standards including eXtensible Access Control Markup Language, XML Encryption, and XML Signature. This integ...

The clinical decision analysis (CDA) has used to overcome complexity and uncertainty in medical problems. The CDA is a tool allowing decision-makers to apply evidence-based medicine to make objective clinical decisions when faced with complex situations. The usefulness and limitation including six steps in conducting CDA were reviewed. The application of CDA results should be done under shared ...