OBJECTIVE Bryonia aspera (Stev. ex Ledeb) is a plant that grows in northeast of Iran. In the present study, cytotoxic and apoptogenic properties of B. aspera root extract was determined against HN-5(head and neck squamous cell carcinoma) and Hela (cervix adenocarcinoma) cell lines. MATERIALS AND METHODS HN-5 and Hela cell lines were cultured in DMEM medium and incubated with different concent...

Objective: Bryonia aspera (Stev. ex Ledeb) is a plant that grows in northeast of Iran. In the present study, cytotoxic and apoptogenic properties of B. aspera root extract was determined against HN-5(head and neck squamous cell carcinoma) and Hela (cervix adenocarcinoma) cell lines. Materials and Methods: HN-5 and Hela cell lines were cultured in DMEM medium and incubated with different concent...

ETHNOPHARMACOLOGICAL RELEVANCE Bryonia dioica Jacq. is a climbing perennial herb with tuberous roots which is widely used in traditional medicine in Algeria for the treatment of cancers; it belongs to the genus Bryonia (Cucurbitaceae). AIM OF THE STUDY To investigate the cytotoxic and apoptogenic activities, the phytochemical composition and acute toxicity of the aqueous extract of Bryonia di...

The Cucurbitaceae genus Bryonia contains ten species that are distributed throughout the Mediterranean to North Africa and from central Europe to Kazakhstan. References to the medicinal uses of species of Bryonia span two millennia, including two passages in Dioscorides’s De Materia Medica, written in about 65 CE. An illustrated copy of this text, known as the Codex Vindobonensis and dated 512 ...

Five common homoeopathic drugs viz., Belladonna, Bryonia, Colchicum, Colocynth and Lathyrus sat were selected and tested against growth and aflatoxin production of Aspergillus flavus. The result indicates that all five drugs suppressed the growth of A. flavus. The lower concentration of all the tested drugs induced maximum growth of fungi and maximum production of aflatoxin. However, the growth...

Dental caries and periodontal diseases have historically been considered the most important global oral health burdens. Many chemicals and synthetic drugs have marked the side effects. Hence, there has been a paradigm shift from the use of modern drugs to the age-old herbs. Achyranthes aspera is one such important plant with various established pharmaceutical properties. The aim of this study w...

Introduction: Leucas aspera is one of the important medicinal plants in Indian medical system and it belongs to Lamiaceae family. Leucas aspera (Willd) Link (L. aspera) belongs to Leucas genus, widely distributed throughout India. L. aspera has many vernacular names and is commonly known as Thumbai. Flavonoid is a phenolic compound which is widely distributed in the plants and responsible for m...