chromosomal appearance of 12 holstein bulls selected for artificial inseminations were examined bysister chromatid exchanges (sces). for differential staining of sister chromatids bromodeoxyuridine (brdu)was inoculated in lymphocyte cultures. the mean, maximum and minimum number of sce per cell weredetermined 6.8 ± 1.14, 8.3 ± 1.1 and 5.7 ± 1.5, respectively. sce frequencies of all animals were...

The growth characteristics of a bromodeoxyuridine-dependent cell line that was derived from a non-contact-inhibited Syrian hamster melanoma line were studied. The dependent cells require high concentrations of bromodeoxyuridine not only for optimal growth but also for the maintenance of the non-contact-inhibited state. When grown in the absence of bromodeoxyuridine, the dependent cells become c...

introduction: this study was designed to investigate the effects of granulocyte colony-stimulating factor (g-csf) administration in rats for 6 weeks after traumatic brain injury (tbi). methods: adult male wistar rats (n = 30) were injured with controlled cortical impact device and divided into four groups. the treatment groups (n = 10 each) were injected subcutaneously with recombinant human g-...

The replacement of thymidine by 5-bromodeoxyuridine in DNA leads to a greatly enhanced stability of chromatin from hepatoma tissue culture or embryonic rat pancreas, as measured by thermal chromatography on hydroxylapatite. The increased stability is directly correlated with the degree of bromodeoxyuridine substitution. On the other hand, the incorporation of bromodeoxyuridine into DNA results ...