BACKGROUND The brine shrimp lethality assay is considered a useful tool for preliminary assessment of toxicity. It has also been suggested for screening pharmacological activities in plant extracts. However, we think that it is necessary to evaluate the suitability of the brine shrimp methods before they are used as a general bio-assay to test natural marine products for pharmacological activit...

In vitro studies were carried out to evaluate the cytotoxic potential of the ethanolic and aqueous extracts of Luffa acutangula against human neuronal glioblastoma cells (U343) and human lung cancer cells (A549). Screening of these extracts was done using the brine shrimp lethality bioassay, MTT assay and SRB assay. The results showed the significant decrease of the viability of the cells in a ...

general toxicity, antiproliferative, antibacterial and antioxidant activities of caulerpa peltata j.v.lamouroux (caulerpaceae) collected from oman sea were investigated. dried, ground alga was soxhlet-extracted with hexane, dichloromethane and methanol successively. the methanol extract was subjected to vacuum liquid chromatography (vlc) fractionation on silica gel using a step gradient of diff...

Water and alcoholic extracts of Crotalaria juncea L. plant were tested for their antimicrobial properties in vitro against some selected human pathogenic bacteria such as Pseudomonas aeruginosa, Escherichia coli, and Staphylococcus aureus by agar well diffusion method and were subjected to brine shrimp lethality assay to detect their cytotoxic ability. In addition, the anticancer properties of ...

Objective: Phytochemical screening as well as several bioassays was performed on the extracts of aerial parts of Caragana jubata. Methods: Extraction of C. jubata was carried out by solvents of increasing polarity. The Phytochemical screening of extracts was carried out using standard procedures. Furthermore, extracts were also evaluated for (i) antibacterial assay, (ii) brine shrimp lethality ...

Medicinal plants constitute important components of flora and are widely distributed in different regions of India. Based on ethnomedical significance, we have collected several medicinal plants used in traditional medicine from Eastern Ghats of India and evaluated for their biological activity. In the present study, a method utilizing brine shrimp (Artemia salina Leach) lethality was used to s...

background and objectives: phlomis olivieri benth. (lamiaceae) is a medicinal plant widely distributed in iran. in the present study, we have investigated the phytochemical constituents, antioxidant activity and general toxicity potential of the aerial parts of this species. methods: silica gel (normal and reversed phases) and sephadex lh-20 column chromatographies were used for isolation of co...

General toxicity, antiproliferative, antibacterial and antioxidant activities of Caulerpa peltata J.V.Lamouroux (Caulerpaceae) collected from Oman Sea were investigated. Dried, ground alga was Soxhlet-extracted with hexane, dichloromethane and methanol successively. The methanol extract was subjected to vacuum liquid chromatography (VLC) fractionation on silica gel using a step gradient of diff...

General toxicity, antiproliferative, antibacterial and antioxidant activities of Caulerpa peltata J.V.Lamouroux (Caulerpaceae) collected from Oman Sea were investigated. Dried, ground alga was Soxhlet-extracted with hexane, dichloromethane and methanol successively. The methanol extract was subjected to vacuum liquid chromatography (VLC) fractionation on silica gel using a step gradient of diff...