background and objectives: phlomis olivieri benth. (lamiaceae) is a medicinal plant widely distributed in iran. in the present study, we have investigated the phytochemical constituents, antioxidant activity and general toxicity potential of the aerial parts of this species. methods: silica gel (normal and reversed phases) and sephadex lh-20 column chromatographies were used for isolation of co...

Cinnamomum species have long been used as spices. The preliminary bioactive constituent’s identification and brine shrimp lethality activities of ethanolic extracts of seven Cinnamomum species viz., C. travancoricum, C. walaiwarense, C. wightii, C. verum, C. sulphuratum, C. riparium, and C. perrottetii were evaluated in this study. The results of cytotoxic activity of the bark extracts of seven...

The investigation was conducted with methanolic fruit extract of Averrhoa carambola for its antibacterial and cytotoxic activities. Antibacterial activity of the extract was evaluated against various Gram-positive and Gram-negative bacteria using disk diffusion technique. For cytotoxic activity, brine shrimp lethality bioassay was performed to estimate LC50 values. In our preliminary screening,...

Objective: To investigate the antifungal, haemolytic and cytotoxic activity of methanol and methanol: chloroform extracts of the marine Mollusks (10 Gastropods, 5 Bivalves, 2 Cephalopods) and 1 Echinoderm. Methods: Crude methanol and methanol: chloroform extracts of the marine Mollusks (10 Gastropods, 5 Bivalves, 2 Cephalopods) and 1 Echinoderm were tested for antifungal activity using disc dif...

Amalakyadi churna is an Ayurvedic formulation, which is extensively used in traditional system of Indian medicine and by folk practitioner for treating all types of fever, and other common ailments In this study, an equal concentration of ethanolic extracts of Amalakyadi churna and its ingredients (50μg/ml of artificial sea water) were subjected to a bioscreening study to detect the cytotoxic a...

Medicinal plants constitute important components of flora and are widely distributed in different regions of India. Based on ethnomedical significance, we have collected several medicinal plants used in traditional medicine from Eastern Ghats of India and evaluated for their biological activity. In the present study, a method utilizing brine shrimp (Artemia salina Leach) lethality was used to s...

Diarrhea is one of the most common causes for thousands of deaths every year. Therefore, identification of new source of antidiarrheal drugs becomes one of the most prominent focuses in modern research. Our aim was to investigate the antidiarrheal and cytotoxic activities of methanolic extract of Maranta arundinacea linn. (MEMA) leaves in rats and brine shrimp, respectively. Antidiarrheal effec...

Medicinal plants constitute an important component of flora and are widely distributed in India. The pharmacological evaluation of substances from plants is an established method for the identification of lead compounds which can leads to the development of novel and safe medicinal agents. Based on the ethnopharmacological literature, several species of medicinal plants used in traditional medi...

In vitro studies were carried out to evaluate the cytotoxic potential of the ethanolic and aqueous extracts of Luffa acutangula against human neuronal glioblastoma cells (U343) and human lung cancer cells (A549). Screening of these extracts was done using the brine shrimp lethality bioassay, MTT assay and SRB assay. The results showed the significant decrease of the viability of the cells in a ...