Background: In this study, Quantitative 32P bremsstrahlung planar and SPECT imaging and consequent dose assessment were carried out as a comprehensive phantom study to define an appropriate method for accurate Dosimetry in clinical practice. Materials and Methods: CT, planar and SPECT bremsstrahlung images of Jaszczak phantom containing a known activity of 32P were acquired. In addition, Phanto...

background: in this study, quantitative 32p bremsstrahlung planar and spect imaging and consequent dose assessment were carried out as a comprehensive phantom study to define an appropriate method for accurate dosimetry in clinical practice. materials and methods: ct, planar and spect bremsstrahlung images of jaszczak phantom containing a known activity of 32p were acquired. in addition, phanto...

BACKGROUND It is unclear how to predict which patients will respond to Y-90 radiosynoviorthesis. The aim of this study is to correlate clinical outcomes following Y-90 radiosynoviorthesis with bremsstrahlung and Y-90 PET/CT imaging findings. METHODS Fifty-one joints underwent bremsstrahlung planar and Y-90 PET/CT imaging following Y-90 radiosynoviorthesis. The Y-90 distribution pattern on bre...

BACKGROUND The purpose of the study is to evaluate whether a pinhole collimator is better adapted to bremsstrahlung single photon emission computed tomography [SPECT] than parallel-hole collimators and in the affirmative, to evaluate whether pinhole bremsstrahlung SPECT, including a simple model of the scatter inside the patient, could provide a fast dosimetry assessment in liver selective inte...

BACKGROUND Yttrium-90 (90Y) positron emission tomography with integrated computed tomography (PET/CT) represents a technological leap from 90Y bremsstrahlung single-photon emission computed tomography with integrated computed tomography (SPECT/CT) by coincidence imaging of low abundance internal pair production. Encouraged by favorable early experiences, we implemented post-radioembolization 90...

Objective(s): Yttrium-90 (90Y) is a beta particle nuclide used in targeted radionuclide therapy which is available to both single-photon emission computed tomography (SPECT) and time-of-flight (TOF) positron emission tomography (PET) imaging. The purpose of this study was to assess the image quality of PET and Bremsstrahlung SPECT by simulating PET and SPECT images of 90Y using Monte Carlo simu...

BACKGROUND the characteristics of (90)Y, suitable for therapy, are denoted by the lack of γ-emission. Alternative methods, using analogues labelled with (111)In or (86)Y, are generally applied to image (90)Y-conjugates, with some inevitable drawbacks. New generation SPECT/CT image systems offer improved Bremsstrahlung images. The intent of this brief communication is to show that high quality (...

Radioembolization (RE) with Yttrium-90 ((90)Y) microspheres is an effective treatment for unresectable liver tumors. The activity of the microspheres to be administered should be calculated based on the type of microspheres. Technetium-99m macroaggregated albumin ((99m)Tc-MAA) single photon emission computed tomography/computed tomography (SPECT/CT) is a reliable assessment before RE to ensure ...

Introduction: Treatment efficacy of radiation therapy using Yttrium-90 radionuclide is evaluated by the bremsstrahlung SPECT imaging following radiation therapy. The radioisotopic images have the ability to provide reliable activity map of 90Y distribution. But these images have a low quantitative accuracy in the 90Y bremsstrahlung SPECT imaging, therefore the optimization of...

BACKGROUND After yttrium-90 ((90)Y) microsphere radioembolization (RE), evaluation of extrahepatic activity and liver dosimetry is typically performed on (90)Y Bremsstrahlung SPECT images. Since these images demonstrate a low quantitative accuracy, (90)Y PET has been suggested as an alternative. The aim of this study is to quantitatively compare SPECT and state-of-the-art PET on the ability to ...