to investigate the effects of the two-pore-domain potassium (k2p) channel task-3 in a syngeneic murine model for malignant glioma. malignant or high-grade glioma (who grade iii and iv) are the most common and most aggressive primary brain tumors in adults. despite aggressive multimodal therapy, the outcome of patients with malignant glioma remains poor. however, recent phase i and ii trials hav...

in this study, 22 patients (15-75 years old) were selected and transferred to ct scan for tumor ablation. for ablations, after prep and drep under the local anesthesia and mild sedation in proper position, small incision made and special needle inserted and guided by proper direction to the core of the tumor. then, laser probe inserted through the needle and laser energy delivered. although we ...

how to cite this article: aghayan golkashani h, hatami h, farzan a, mohammadi hr, nilipour y, khoddami m, jadali f. tumors of the central nervous system: an 18-year retrospective review in a tertiary pediatric referral center. iran j child neurol. summer 2015;9(3):24-33.   abstract objective few studies exist on the demographics and trends of pediatric central nervous system (cns) tumors in ira...

background and objective: gliomas are the most common primary brain tumors. despite therapeutic advances, the majority of gliomas do not respond to either chemo or radiotherapy. cd117, the gene product of c-kit has been expressed in cells of glial tumors. because gastrointestinal stromal tumors (gists) that express cd117 respond dramatically to treatment with tyrosine kinase inhibitors, identif...

background and purpose: cancer and cerebrovascular accidents (cva) are two most common causes of mortality and morbidity in the elderly. patients with brain tumor can be highly affected by postsurgical stroke. cva may be the first manifestation in these patients . therefore, we aimed to assess the epidemiological factors affecting cva after brain surgery. methods: in this cross-sectional study ...

abstract background: in vivo measurements of applied dose during radiotherapy treatment, is important to ensure accurate dose delivery to patients. uncertainty in dose delivery should fall within ±5% of the prescribed dose as recommended by icru. assessment of dose for radiotherapy applications performed with various types of detectors. in this study, semiconductor diodes were used which have s...

introduction bnct is an effective method to destroy brain tumoral cells while sparing the healthy tissues. the recommended flux for epithermal neutrons is 109 n/cm2s, which has the most effectiveness on deep-seated tumors. in this paper, it is indicated that using d-t neutron source and optimizing of beam shaping assembly (bsa) leads to treating brain tumors in a reasonable time where all iaea ...

introduction: during radiotherapy, high accuracy in the dose delivery is required because there is a strong  relationship between the absorbed dose, local tumor control and particularly the normal tissue damage. in  many institutions, in vivo dosimetry using diodes is performed to check the actual dose delivered. in general,  the uncertainty in the dose delivered should fall within  ± 5% of the...

Brain tumors, which is one of the destructive forms of human being’s cancers, are the second most common children’s cancers. Brain tumors may have an inherited (small percent), acquired reasons due to environmental factors. Nowadays advances in cosmetic industry have increased our ability in the field of youth and beauty. Hair dye products are such innovations. Recent studies showed...

brain tumors in elderly are increasing as the number of people, who comprise the older population, does.about half of the patients with brain tumors appear to be over 60 years of age.in this review article, glioblastoma multiform, as the most common malignant tumor of the central nervous system in elderly is discussed in details of definition, prognosis, diagnosis, treatment and differential di...