The impact of card cylinder speed, card production rate and draw frame doubling on cotton yarn quality parameters was investigated by using the BoxBehnken experimental design. It was found that yarn tenacity, elongation and hairiness increase by increasing the number of draw frame doubling up to a certain level and then decrease by further increase in doubling. Yarn unevenness increased by incr...

Dye concentration of waste water can lead to a variety of problem. Biosorption has been proved to be a well established and cheap pollutant removal process among other purification techniques in this study our aim is to find the optimization of methylene blue by the spent biomass of Aspergillus terreus using response surface methodology. The spent biomass was received as a free sample from Kreb...

The objective of the research is to study and compare response surface designs: Central composite designs (CCD), BoxBehnken designs (BBD), Small composite designs (SCD), Hybrid designs, and Uniform shell designs (USD) over sets of reduced models when the design is in a spherical region for 3 and 4 design variables. The two optimality criteria ( D and G ) are considered which larger values imply...

Based on a BoxBehnken design,response surface methodology was used to optimize the effects of processing parameters of extraction from Scutellaria barbata on total alkaloids yield. Three independent variables such as extraction time (X1), liquid-solid ratio (X2) and ultrasonic frequency (X3) were study. The P-value indicated that both extraction time (X1) and ultrasonic frequency (X3) had signi...

The present study aims to enhance the bioavailability of Blueberry by formulating it as nanosuspension. mainly consists ofanthocyanins which have strong antihyperlipidemic activity but suffers from low causes hindrances in itstherapeutic treat hyperlipidemia. Hence improve its bioavailability, nanosuspension blueberry was prepared. BoxBehnken design applied predict effect independent variables ...

Nisin is a bacteriocin approved in more than 50 countries as a safe natural food preservative. Response surface methodology (RSM) combined with artificial neural network-genetic algorithm (ANN-GA) was employed to optimize the fermentation medium for nisin production. Plackett-Burman design (PBD) was used for identifying the significant components in the fermentation medium. After that, the path...

The purpose of this work was to develop and characterize a vesicular drug carrier for topical delivery of Quetiapine to overcome the problems related with oral route that is high first pass metabolism and fluctuating drug plasma concentration. The effects of key formulation variables on entrapment efficiency (EE %), vesicle size and in vitro drug permeation were studied using a BoxBehnken desig...

The aim of this study was optimization of the conditions for the production of alkaline protease from the Bacillus strains coded as L18, L21 and I18, which were isolated from our natural habitats. Additionally, the goal was also to optimize the production of alkaline protease from Bacillus sp. L21 in a new low-cost media formulation by employing design of experiments and response surface method...