the purpose of this study was to evaluate the efficacy of two types of bone substitutes, bio-oss and nuoss, for repair of bone defects.this study was performed on the calvaria of 14 new zealand rabbits. the 6mm critical size defect (csd) models of bone regeneration were used. three csds were created in each surgical site. the first defect was filled with nuoss, the second one with bio-oss and t...

statement of problem: reconstruction methods are an essential prerequisite for functional rehabilitation of the stomatognathic system. platelet-rich plasma (prp) offers a new and potentially useful adjunct to bone substitute materials (e.g. xenografts) in oral and maxillofacial bone and implant reconstructive surgery. purpose: an animal study was carried out to investigate the influence of prp ...

both anorganic bovine bone (abb) and β-tricalcium phosphate (β-tcp) are used in clinical practice as bone substitute materials, but there is limited data comparing these two materials in standardized defects. the aim of this study was to histologically evaluate the effectiveness of abb and β-tcp in the healing of experimentally induced bone defects.eighteen bone defects were created on the calv...

introduction : deproteinized bovine bone mineral (bio-oss) is a xenogenic bone substitute, widely used in maxillofacial bone regeneration. the aim of this in vitro study was to investigate its influence on the growth behavior of human osteosarcoma cell line, saos-2 culture, and compare it with the physiologic dose of dexamethasone, an inductive factor for osteoblasts. materials and methods: hum...

the objective of this study was to evaluate the effect of accell connexus(®) on the quality and rate of healing in experimental defects of rabbit calvarium compared to bio-oss®.twelve 2.5-3.5 kg weighing new zealand white rabbits were used. three defects (3×6 mm) were created in the cranium of the animals subsequently filled with accell connexus(®), bio-oss® or served as controls. the animals w...

conclusions alendronate may be considered a therapeutic option for improving the bone formation process and reducing resorption in different bone grafting procedures. further detailed studies should focus on dosage and time-dependent effects of alendronate on bone remodeling. results at 6 weeks, the bone area was significantly larger in the xenograft-alendronate group (33.0% ± 5.0%) than in the...

  Background: Ligament reconstruction is a common procedure in orthopedic surgery. Although several popular techniques are currently in use, new methods are proposed for secure fixation of the tendon graft into the bone tunnel. Purposes: We sought to introduce our new technique of Bashti bone plug for fixation of soft tissue graft in anterior cruciate ligament (ACL) reconstruction and to compar...

Autogenous bone graft is gold standard in treating bone defects, but it might have difficulty in corporation and rejection reaction. This study is to compare the effectiveness among freeze-dried xenograft, freeze-dried allograft, hydroxyapatite xenograft, and demineralized bone matrix xenograft as bone graft to fill bone defect in femoral diaphysis of white rabbit. Thirty male New Zealand white...