Recently, Functionally Graded Scaffolds (FGSs) have attracted a lot of attention as bone replacements due to their gradient porosities as well as a bone structure. In present study titanium functionally graded scaffolds (FGSs) were fabricated by powder metallurgy route using Mg and carbamide as space holders. The arranged layers with 20, 40 and 60 Vol.% porosities were compacted in steel die us...

Restoring normal function and appearance after massive facial injuries with bone loss is an important unsolved problem in surgery. An important limitation of the current methods is heuristic ad hoc design of bone replacements by the operating surgeon at the time of surgery. This problem might be addressed by incorporating a computational method known as topological optimization into routine sur...

Engineered Vascularized Flaps In article number 2008687, Shulamit Levenberg and co-workers fabricate composite neo-tissue flaps by combining polymeric matrices decellularized bone. These are perfused in vivo using hosts via a potent neo-vascular network. imaging is utilized to show how support long-term bone repair vascularization. This methodology may one day replace autologous tissue harvest ...

We matched 78 patients with a loose cemented Charnley Elite Plus total hip replacement (THR) by age, gender, race, prosthesis and time from surgery with 49 patients with a well-fixed stable hip replacement, to determine if poor bone quality predisposes to loosening. Clinical, radiological, biomechanical and bone mineral density indicators of bone quality were assessed. Patients with loose repla...

The aims of this study were to determine the complexity of surgery required to revise failed unicompartmental knee replacements and to evaluate the outcome following revision. Between 2000 and 2009, 494 cemented Oxford phase 3 medial unicompartmental knee replacements were implanted, with 24 (4.9%) requiring revision (mean age: 63.5 years; 58% male). Mean time to revision was 3.0 years. All cas...

The authors report their experience in the management of a 53-year-old woman with rheumatoid arthritis who presented with bilateral asynchronous traumatic periprosthetic fractures of the humerus after bilateral elbow replacements. One side was treated with a long-stem revision and internal fixation with bone graft, while the other side was treated with a long-stem distal humeral replacement. Sh...

Significant advances have been made in bone tissue engineering (TE) in the past decade. However, classical bone TE strategies have been hampered mainly due to the lack of vascularization within the engineered bone constructs, resulting in poor implant survival and integration. In an effort toward clinical success of engineered constructs, new TE concepts have arisen to develop bone substitutes ...

Introduction. The loss of the jaw bone, especially in area alveolar process, can significantly complicate procedure prosthetic rehabilitation patients. reason for bones are physiological and pathological processes. Materials. Bone replacements widely used reconstruction bone defects. optimal characteristics these materials biocompatibility, bioinertness, biofunctionality a special canalicular i...

Impaction allografting is an attractive procedure for the treatment of failed total hip replacements. The graft-cement-host bone interface after impaction allografting has not been characterized, although it is a potential site of subsidence for this type of revision total hip reconstruction. In six human cadaveric femurs, the cancellous bone was removed proximally and local diaphyseal lytic de...