نتایج جستجو برای: Bone marrow stem cells

تعداد نتایج: 1737579  

Journal: :archives of trauma research 0
serkan akpancar department of orthopedic surgery, gulhane military hospital, ankara, turkey; department of orthopedic surgery, gulhane military medicine academy, ankara, turkey. tel: +90-5443229700, fax: +90-3124045500 oner tatar department of orthopedic surgery, air force academy kasımpaşa military hospital, istanbul, turkey hasan turgut department of orthopedic surgery, bursa military hospital, bursa, turkey faruk akyildiz department of orthopedic surgery, gulhane military hospital, ankara, turkey safak ekinci department of orthopedic surgery, agri military hospital, agri, turkey

conclusions large amounts of preclinical studies have been made of stem cells and there is an increasing interest to perform these studies within the human population but preclinical studies are insufficient; therefore, much more and efficient studies should be conducted to evaluate the efficacy and safety of stem cells. context musculoskeletal injuries may be painful, troublesome, life limitin...

Journal: :international journal of reproductive biomedicine 0
karim nayernia jae ho lee wolfgang engel jessica nolte nadja drusenheimer kristina rathsack

germline and somatic stem cells are distinct types of stem cells that are dedicated to reproduction and somatic tissue regeneration, respectively. germline stem cells (gscs), which can self-renew and generate gametes, are unique stem cells in that they are solely dedicated to transmit genetic information from generation to generation. we developed a strategy for the establishment of germline st...

Journal: :iranian journal of basic medical sciences 0
zolikha golipoor school of medicine, tehran university of medical sciences, tehran, iran iraj ragerdi kashani school of medicine, tehran university of medical sciences, tehran, iran mohammad akbari school of medicine, tehran university of medical sciences, tehran, iran gholamreza hassanzadeh school of medicine, tehran university of medical sciences, tehran, iran fatemeh malek school of medicine, tehran university of medical sciences, tehran, iran reza mahmoudi school of medicine, yasouj university of medical sciences, yasouj, iran

objective(s) bone marrow is the traditional source of human multipotent mesenchymal stem cells (mscs), but adipose tissue appears to be an alternative and more readily available source. in this study, rat adipose-derived stem cells (adscs) were induced to differentiate into schwann-like cells and compared with rat bone marrow stem cells (bmscs) for their schwann-like cells differentiation poten...

Journal: :iranian biomedical journal 0
keywan mortezaee parichehr pasbakhsh iraj ragerdi kashani fatemeh sabbaghziarani ameneh omidi adib zendedel

background: bone marrow-derived mesenchymal stem cells (bmmscs) transplantation has been considered as a promising milestone in liver fibrosis treatment. however, low amounts of homing are a major obstacle. we aimed to investigate the role of melatonin pretreatment in bmmsc homing into experimental liver fibrosis. methods: bmmscs were obtained, grown, propagated and preconditioned with 5 µm mel...

Journal: :anatomical sciences journal 0
narges talebian kazem parivar laya kafami mohsen marzban maryam shirmohammadi mohammad taghi joghataei

introduction: bone marrow (bm) is a known source of mesenchymal stem cells (mscs) that are used for cell therapy. this study attempts to identify if the wharton’s jelly (wj) is a suitable substitute for bm as a source for mscs. materials and methods: a population of human wj and bm stem cells were isolated and incubated with fluorescein conjugated antibodies for five specific msc markers. cell ...

Journal: :molecular and biochemical diagnosis (journal) 2014
safoura khajeniazi khajeniazi maryam shahrabi farahani masoud soleimani

background: in recent years we have successfully adopted an in vitro hepatogenic differentiation of mesenchymal stem cells (mscs). in this protocol the biologically active hepatocyte-like cells were differentiated from the stem cells isolated from either bone marrow or umbilical cord blood (ucb) samples. the aim of the present study was to compare the efficiency of the hepatogenic differentiati...

Journal: :international journal of hematology-oncology and stem cell research 0
naser mobarra department of clinical biochemistry, school of medicine, tehran university of medical sciences, tehran, iran ; students'sciences research center, tehran university of medical sciences, tehran, iran. masoud soleimani department of hematology, school of medical sciences, tarbiat modares university, tehran, iran. fatemeh kouhkan department of molecular biology and genetic engineering, stem cell technology research center, tehran, iran. zahra hesari department of pharmaceutics, faculty of pharmacy, tehran university of medical sciences, tehran, iran. reyhaneh lahmy department of genetics, faculty of biological sciences, tarbiat modares university, tehran, iran. majid mossahebi-mohammadi department of hematology, school of medical sciences, tarbiat modares university, tehran, iran.

background: the use of stem cells is considered as an appropriate source in cell therapy and tissue engineering. differentiation of human induced pluripotent stem cells (hipscs) to hepatocyte-like cells (hlcs) on mouse embryonic fibroblasts (mefs) feeders is confronted with several problems that hinder the clinical applications of these differentiated cells for the treatment of liver injuries. ...

Journal: :iranian biomedical journal 0
علی اکبر موثق پور ali akbar movassagh pour مژده صالح نیا mojdeh salehnia علی اکبر پورفتح ا... ali akbar pourfatollah مسعود سلیمانی masoud soleimani

the aim of this study was to isolate mouse embryonic stem cells from late blastocyst stage embryos and to use them as a model system for the study of hematopoietic induction outside the embryo by coculturing of embryonic stem cells with bone marrow stromal cells. blastocyst stage embryos from pregnant nmri mice were obtained and cultured for 1-2 days in dmem medium. the inner cell masses formed...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه علوم پایه دامغان 1389

هم کشتی سلول های بنیادی با یکدیگر دریچه های جدیدی را فرا روی محققین علم سلول درمانی گشوده است. با این روش میتوان سبب بهبود شرایط کشت و تمایز بهتر سلول های بنیادی شد. فاکتورهای رشد عصبی (neurotrophic factors,ntfs)، مولکول هایی هستند که نقش های بسیار حیاتی در بقا، تکثیر و تمایز سلول های بنیادی دارند. هدف از این تحقیق ارزیابی بیان فاکتورهای نوروتروفیک (‎‎‎‎gdnf‎‎، ‎bdnf‎، ‎‎‎cntf‎،nt3) و سرعت تکثی...

Journal: :cell journal 0
mehdi kadivar neda memari pezhman fard-esfahani

background: the aim of this study was optimization of the polyfect gene delivery method of pcdna3.1 expression vector transfected with the mouse pdx-1 gene in three different kinds of mesenchymal stem cells and hepa cells as well as comparison of transfection efficiency leading to expression of the mentioned gene in the cell types used. materials and methods: rat bone marrow-derived mesenchymal...

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