objective(s): the aim of this study was to observe the influence of phytoestrogen α-zearalanol on ovariectomy-induced postmenopausal osteoporosis in rats. materials and methods:40 sd female rats were randomly divided into four groups: sham group, ovx group (ovariectomized and fed estrogen), α-zearalanol group (ovariectomized and fed α-zearalanol) and untreated group (ovariectomized). three week...

PURPOSE Micro-computed tomography (micro-CT) has been widely used in the evaluation of regenerated bone tissue but the reliability of micro-CT has not yet been established. This study evaluated the correlation between histomorphometric analysis and micro-CT analysis in performing new bone formation measurement. METHODS Critical-size calvarial defects were created using a 8 mm trephine bur in ...

The aim of this study was to determine the pattern of bone remodeling after maxillary sinus lifting in humans by means of fractal dimension (FD) and histomorphometric analysis. Therefore, the correlation between FD and the histomorphometric findings was evaluated. Sixteen patients with posterior edentulous maxilla were enrolled in this study. Maxillary sinus lifting was performed using autogeno...

statement of problem: reconstruction methods are an essential prerequisite for functional rehabilitation of the stomatognathic system. platelet-rich plasma (prp) offers a new and potentially useful adjunct to bone substitute materials (e.g. xenografts) in oral and maxillofacial bone and implant reconstructive surgery. purpose: an animal study was carried out to investigate the influence of prp ...

BACKGROUND Direct metal laser sintering (DMLS) is an additive manufacturing technique that allows the fabrication of dental implants layer by layer through the laser fusion of titanium microparticles. The surface of DMLS implants is characterized by a high open porosity with interconnected pores of different sizes; therefore, it has the potential to enhance and accelerate bone healing. To date,...

background: decalcified freeze-dried bone allograft (dfdba) may have the potential to enhance bone formation around dental implants. our aim in this study was the evaluation and comparison of two types of dfdba in treatment of dehiscence defects around euroteknika ® implants in dogs.     methods: in this prospective clinical trial animal study, all mandibular premolars of three iranian dogs wer...

BACKGROUND A study was designed to quantify the extent of porous osseointegration at the prosthesis-bone interface in the Prestige LP prosthesis containing a plasma-sprayed titanium coating. METHODS Using an anterior surgical approach, cervical disc arthroplasty was performed in 8 mature male goats at the C3-C4 segment, followed by implantation of the Prestige LP prosthesis. The vertebral spe...

the aim of this study was to compare the lateral window and osteotome techniques for sinus lifting using histological and histomorphometric methods.in this clinical trial 10 patients (a total number of 14 sinus areas) who needed implant treatment in the atrophic posterior maxilla were enrolled. in all the cases the residual bone height between the sinus floor and the alveolar crest was less tha...

Bone microstructure has usually been assessed by obtaining samples invasively and analyzing them with conventional histomorphometric methods. Improvements in high-resolution image acquisition systems have enabled non-invasive assessment of bone morphology and a more precise 3-D evaluation by means of "virtual biopsies", permitting bone assessment in regeneration or remodeling processes. This re...