blue nevi are uncommon, asymptomatic lesions of the uterine cervix. these lesions are not often detected clinically or on colposcopy. careful histopathological examination is required. the nevus cells are said to originate from the immature melanoblasts of the neural crest. these lesions need to be differentiated from malignant melanoma and melanosis of the cervix. we present here a case report...

Melanomas can arise either de novo (70%) or from pre-existing melanocytic lesions (30%). Of the latter, most cases arise at the dermoepidermal junction from small congenital or acquired non-blue nevi while only a few arise from blue nevi, notably the cellular subtype and less commonly the common (dendritic) type. Melanomas that arise from blue nevi usually occur on the scalp with greater freque...

Purpose To evaluate BRAF, NRAS, and GNAQ mutations in surgical specimens of common and blue conjunctival melanocytic nevi. Methods Surgical specimens from 25 conjunctival melanocytic nevi (23 common and 2 blue) of 25 patients were evaluated. All common nevi were analyzed immunohistochemically for the expression of BRAF V600E or NRAS Q61R. One lesion with negative immunoreactivity and for all ...

A 52-year-old White man presented with a dozen small, well-restricted, punctiform, asymptomatic, blue-gray macules on the left shoulder. A few months earlier, he had been treated with oral acyclovir for herpes zoster (HZ) affecting the left C7-C8 dermatomes. All the blue macules appeared over a short period of time and then remained stable. The patient had not experienced any previous trauma or...

In this report, we examine several morphologic aspects of blue nevi of internal organs, and compare them to similar conditions of the skin. From a morphologic point of view, blue nevi of internal organs are more similar to the so-called dermal melanocytoses. Nevertheless, since melanocytoses and blue-nevi seem to have the same benign prognosis, and since blue nevus is a historically consolidate...

Combined melanocytic nevi are composed of 2 or more distinct populations of nevomelanocytes. Most commonly used to describe the combination of blue nevi with common nevi, it may also be applied to other combinations of benign melanocytic proliferations, including Spitz nevi and nevi with deep dermal pigmented nevomelanocytes. We report the incidence and distribution of these tumors at the Massa...

Blue nevi are dermal dendritic melanocytic proliferations presenting as papules, nodules or plaques of blue, blue-gray or blue-brown color. Dermoscopic appearance commonly shows global patterns as homogeneous mono/dichromatic pigmentation and multichromatic pigmentation. Here, we report the case of a blue nevus with the dermoscopic feature of peripheral streaks with branches. With histopatholog...

PURPOSE To report the clinical and histologic features of combined nevi of the conjunctiva, a type of nevus that is not uncommon in the skin but has rarely been reported in the conjunctiva. METHODS Conjunctival nevi and melanomas from the files of the University of California, San Francisco, eye pathology laboratory were reviewed from 1984 to 1999 for the presence of features of both standard...

OBJECTIVE To determine the prevalence, morphologic characteristics, associations, and frequency of features reported to predict growth of choroidal nevi in a large population-based sample. METHODS A total of 3654 subjects aged 49 to 97 years participating in the Blue Mountains Eye Study had a detailed eye examination, including photography of 6 standard retinal fields. Nevi were graded from p...