Background: Long-term use of levofloxacin can cause alterations in the liver function. This study aimed to determine the protective effect of black seed oil (BSO) against liver injury due to levofloxacin administration in rats. Methods: The chemical composition of BSO was analyzed with gas chromatography and mass spectrophotometry (GC-MS). Rats (n=30) were treated daily with levofloxacin and ...

Background: New therapies for toxoplasmosis are critically needed. Nigella sativa, commonly known as black seed or black cumin, has been known to include many medicinal properties. It has anti-inflammatory, and immuno-potentiating effects, antihelminthic and antiprotozoal activities. Objective: To study the effect of black seed oil (BSO) from Nigella sativa against Toxoplasma gondii Me49 strain...

Nuclear factor erythroid 2-related factor 2 (Nrf2) is one of the transcription factors involved in providing endogenous antioxidants. Black seed oil (BSO), suspected have antioxidant effects that can be used to modulate the expression and levels of Nrf2. The study aims to determine the effect of BSO as adjuvant therapy on levels of Nrf2 to the patients with metabolic syndrome risk. The re...

Background: The high saturated fatty acid content of beef has been linked to obesity and cardiovascular diseases. study investigated the impact black seed oil (BSO) on fat-altered hemato-biochemical pathophysiological alterations in albino mice. Methods: Twenty four Swiss Albino mice (Mus musculus) 25-28 days old were equally divided into three groups (n=8) namely A, B C. Mice group A was desig...

twenty pregnant buffaloes, eight weeks before the expected calving date, were assigned into two homogeneous groups of 10 animals each, according to their season of lactation (2nd to 8th season of lactation); the first group (g1) were fed on a ration consisting of concentrate feed mixture (22% yellow corn, 35% cotton seed meal, 33% wheat bran, 4% rice bran, 3% molasses, 2% limestone and 1% sodiu...

Background: Cisplatin (CP) is an anticancer agent with various side effects, including duodenal mucosal damage. It well known that black seed oil (BSO) and honey (H) are rich in antioxidants have a protective effect. Purposes: To determine the effect of BSO H combination on histopathology rats given CP exposure. Methods: Randomized post-test-only control group design was used this study. A tota...

Background & Aim: Black seed or black cumin (Nigella sativa L.) belongs the family Ranunculaceae. Black seed is one of these species, which is naturally distributed in different parts of the country. It is extensively cultivated in various regions of Iran.  Experimental: The experiment was achieved using randomized complete block desi...

background: several formulations of the nigella sativa l. seeds (black seed) have been used in traditional medicine for treatment and prevention of a wide range of diseases including diabetes. but blood glucose lowering effects of its oil in a clinical study is of an interest. objective: the present study was undertaken to explore the possible blood glucose lowering effects of the black seed oi...

Background & Aim: Black seed or black cumin (Nigella sativa L.) belongs the family Ranunculaceae. Black seed is one of these species, which is naturally distributed in different parts of the country. It is extensively cultivated in various regions of Iran.  Experimental: The experiment was achieved using randomized complete block desi...