background due to a recent alarming increase in the number of hiv-hcv co-infected patients in romania. objectives a cross sectional study was conducted to assess the baseline predictors of liver disease evolution. patients and methods 83 hiv-hcv co-infected patients, untreated for hcv infection, were evaluated for viral replication, liver fibrosis (estimated by a noninvasive marker - fib4), and...

historically, biomarkers have been used in two major ways to maintain and improve better health status: first, for diagnostic purposes, and second, as specific targets to treat various diseases.   a new era in treatment and even cure for the some diseases using reprograming of somatic cells is about to be born. in this approach, scientists are successfully taking human skin cells (previously co...

background: the present study was carried out on the human population of kashmir valley to evaluate the status of the biochemical parameters of infected population. materials and methods: blood samples were collected from 514 individuals, 298 (57.97%) males and 216 (42.02%) females, 187 (36.38%) were found sero-positive for human toxocariasis. results: alkaline phosphatase level was found highe...

the clinical behavior of asthma varies with age at onset. this study was undertaken to identify associated markers of adult-onset allergic asthma (age ≥20 years).this cross-sectional study compared two groups: 58 patients with asthma onset at <20 years and 66 with onset at ≥20 years. they were compared depending on results of clinical history, and body mass index (bmi), aeroallergen sensitizati...

conclusions this study on a limited number of patients treated with adjutant anthracyclins-based regimens, revealed that her2/neu is not a unique strong predictor for outcome, thus according to combination of her2/neu status and other clinical factors, it is necessary to distinguish patients at high risk of recurrence. results her2/neu amplification was identified in 19 (38%) of 50 patients. no...

conclusions according to the results obtained in our study, advanced age, higher bmi, ast, alt, and hbv-dna levels, and low albumin and platelet levels are correlated with advanced fibrosis in patients with chb. objectives this study evaluated the correlation between hepatic fibrosis and routine laboratory values in patients with chronic hepatitis b. patients and methods the files of 456 patien...

background: aflatoxins are found in the most types of foods such as corn, peanuts, pistachio, rice, milk, and etc. these toxins may cause several adverse health effects, notably cancer. the main aim of this study was to evaluate excretion level of aflatoxin m1 (afm1), as a biomarker of aflatoxin b1 exposure, in urine samples of iranian population. also, relationship between diet and urinary exc...

background: cornus mas l, an olive-shaped red-colored single-seeded fruit, is used in traditional medicine in different parts of europe and asia. objectives: in the present study, 40 male wistar rats were randomly divided into five groups, and the effects of 21 days of intraperitoneally (ip) administration of 50, 200 and 400 mg/kg body weight of c. mas hydro-methanolic extract on the rats hemat...