We describe a new practical capillary electrophoresis/electrospray ionization-mass spectrometry (CE/ESI-MS) method for the forensic analysis of phosphorus-containing amino acid-type herbicides, glyphosate (GLYP), glufosinate (GLUF) and bialaphos (BIAL). A new sheathless interface, a high sensitivity porous sprayer (HSPS), was used in this study. The limits of detections of GLYP, GLUF and BIAL w...

Disclosure: Prof Heinz Reichmann received research grants and compensation for his involvement on advisory boards and lectures from Abbott, Abbvie, Bayer Health Care, BIAL, Boehringer/Ingelheim, Brittania, Cephalon, Desitin, GSK, Lundbeck, Medtronic, Merck-Serono, Novartis, Orion, Pfizer, TEVA, UCB Pharma, Valeant, and Zambon. Prof Werner Poewe has received honoraria for lectures and consultanc...

A novel absolute determination method using chirality without any calibration curves or comparison standards has been proposed for phosphorus-containing amino acid-type herbicides, glufosinate (D,L-GLUF) and bialaphos (BIAL). This method is based on a change in the enantiomeric ratio after the spiking of a known amount of the enantiomers with different enantiomeric ratios to a sample. D,L-GLUF ...

in the present study, seven isolates of haemophilus influenzae type b were cultured in four different media to compare growth rate and capsule production. four liquid media namely brain heart infusion broth (bhi), trypticase soy broth (tsb), mueller hinton broth (mhb) and gonococci broth (gc) with added supplements (1% hemoglobin, 1% isovitalex) were used. the growth was measured by colony coun...

TOPIC: Pulmonary Vascular Disease TYPE: Original Investigations PURPOSE: To investigate the carvedilol-mediated P-gp transporter inhibition on pharmacokinetics (PK) of zamicastat and its metabolites, to safety tolerability zamicastat, when administered alone concomitantly with carvedilol. METHODS: Open-label, 2-periods, fixed-sequence study in 41 healthy subjects assess PK single-dose 200 mg, c...

A 47-year-old Caucasian woman had a pruriginous dermatitis involving her axillary, infra-mammary and inguinal flexures, and the lateral aspects of her trunk. Confluent erythematous patches without epidermal detachment were observed, sparing the extremities and mucous membranes (Fig. 1). There were no systemic symptoms. A week before the onset of dermatitis, she was started on aminocaproic acid ...