The microgravity experienced during space flight induces physiological changes that affect astronauts' health and performance. Simulations such as prolonged bed rest can mimic some of these changes and provide study conditions that are more accessible than during space flight itself. Previous studies, including several long and short-term bed-rest campaigns supported by ESA, have yielded signif...

background: coronary angiography is frequently applied for diagnostic purposes in patients with coronary artery disease. be that as it may, there is still no consensus about the optimal time for the ambulation of patients following femoral arterial puncture. we sought to compare 6 hours of complete bed rest and 2 hours of complete bed rest in patients after angiography. methods: this randomized...

We analyzed the effects of gravitational unloading on muscular fatigability and the effectiveness of resistive vibration exercise to counteract these changes. Changes in knee extensor fatigability as a consequence of 8 weeks of horizontal bedrest with or without daily resistive vibration exercise were evaluated in 17 healthy male volunteers. Bedrest increased fatigability (% decrease in maximal...

The pharmacokinetics of ibuprofen were studied under microgravity (µG) conditions and compared with those at normal gravity (1G) in humans. Six healthy human volunteers were given 600 mg oral dose ibuprofen during 1-day simulated µG antiorthostatic bed rest position, then at normal position (1G) in a sequential design with 7 days washout time. Saliva and plasma samples were obtained up to 8 hou...

This month, we focus on current research in bed rest in pregnancy. Dr. Lorenz discusses four recent publications, and each is concluded with a "bottom line" that is the take-home message. The complete reference for each can be found in on this page, along with direct links to the abstracts.

This work studied the influence of effluent recirculation upon the kinetics of anaerobic degradation of dairy wastewater in the feedless phase of intermittent upflow anaerobic sludge bed (UASB) reactors. Several laboratory-scale tests were performed with different organic loads in closed circuit UASB reactors inoculated with adapted flocculent sludge. The data obtained were used for determinati...