نتایج جستجو برای: BMIPP

تعداد نتایج: 159  

Journal: :Annals of nuclear medicine 2003
Chunlei Zhao Noriyuki Shuke Atsutaka Okizaki Wakako Yamamoto Junichi Sato Yukio Ishikawa Takafumi Ohta Naoyuki Hasebe Kenjiro Kikuchi Tamio Aburano

OBJECTIVE To investigate myocardial fatty acid metabolism and its relationship with left ventricular (LV) function and perfusion in hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM). METHODS Thirty-nine patients with cardiomyopathies (58 +/- 14 y), comprising 15 DCM and 24 HCM, and 9 age-matched healthy controls were studied with 123I-15-(p-iodophenyl)-3-(R,S)-methylpentadeca...

Journal: :Kaku igaku. The Japanese journal of nuclear medicine 2001
K Ito H Sugihara T Tanabe T Yuba T Doue Y Adachi S Katoh A Azuma M Nakagawa

PURPOSE We studied the effect of myocardial ischemia and diabetes mellitus (DM) on the myocardial fatty acid metabolism using 123I-BMIPP myocardial scintigraphy. METHODS We performed 123I-BMIPP myocardial scintigraphy in 50 patients with myocardial ischemia and without DM (AP), in 30 patients with myocardial ischemia and DM (AP + DM), 12 patients with DM and without myocardial ischemia (DM), ...

Journal: :Journal of cardiology 2001
F Inoue T Hashimoto S Uemura A Kawamoto K Dohi A Matsushima

OBJECTIVES This study investigated retardation of abnormal uptake of iodine-123-beta-methyl-p-iodophenyl-pentadecanoic acid(BMIPP) scintigraphy in patients with vasospastic angina. METHODS Twenty-three patients with vasospastic angina showed abnormal uptake of BMIPP before medical treatment and had coronary vasospasm induced by acetylcholine. The patients were divided into two groups accordin...

Journal: :Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1997
R Hosokawa R Nohara Y Fujibayashi K Okuda M Ogino T Hata M Fujita N Tamaki J Konishi S Sasayama

UNLABELLED To evaluate the clinical utility of 123I-(rho-iodophenyl)-3-R,S-methylpentadecanoic acid (123I-BMIPP) for ischemic heart disease, we investigated the metabolic fate of 123I-BMIPP in canine models with mild and severe ischemia and evaluated the clinical utility of this tracer. METHODS Using open-chest dogs under anesthesia, we assembled a system that would release all the blood from...

Journal: :Annals of nuclear medicine 2000
E Tsujimura H Kusuoka K Fukuchi S Hasegawa K Yutani M Hori S Hirono T Izumi T Nishimura

To elucidate the change in perfusion and aerobic metabolism in myocarditis, tissue counting and dual tracer ex vivo autoradiography with Tl-201 and a free fatty acid analog, I-123- or I-125-labeled (p-iodophenyl)-methyl-pentadecanoic acid (BMIPP), were performed in rats with myocarditis induced by immunization with cardiac myosin. Inflammatory damage was classified histologically. At the acute ...

Journal: :Circulation journal : official journal of the Japanese Circulation Society 2003
Ryu Sasaki Isao Mitani Takashi Usui Yutaka Kitamura Yuzuru Yoshii Toshiyuki Ishikawa Kazuaki Uchino Nobukazu Takahashi Kazuo Kimura Satoshi Umemura

In the present study, the effectiveness of 123I-beta-methyliodophenyl pentadecanoic acid (BMIPP) single photon emission computed tomography (SPECT) for predicting cardiac death of patients with chronic heart failure was evaluated. Abnormalities of fatty acid metabolism are found in patients with chronic heart failure and BMIPP was developed as a tracer for scintigraphic assessment of myocardial...

Journal: :Kaku igaku. The Japanese journal of nuclear medicine 2005
Hayato Mitsuyama Masahiro Abe Hitoshi Iino Manabu Fujinawa Akira Yamashita

OBJECTIVES The feasibility of long-term outcome prediction using BMIPP myocardial scintigraphy was evaluated in cases of acute myocardial infarction. METHODS BMIPP myocardial scintigraphy was performed on 165 patients with first acute myocardial infarction at the time of discharge from the hospital (average of 27 days after disease on set). Discordance between early and delayed image was chec...

2017
Ryosuke Tashiro Noriko Onoue Hiroya Rikimaru Kenichi Tsukita Hiroshi Fujita Nobuhiro Yamaguchi Takeshi Ishizuka Yasushi Suzuki Hiroyoshi Suzuki Tsuyoshi Shinozaki

A 42-year-old man was referred to our hospital due to chest pain, diabetes mellitus, and sensorineural hearing loss. Transthoracic echocardiography revealed diffuse left ventricular hypokinesis. He was diagnosed with mitochondrial disease and a c.A3243G mutation was identified in his mitochondrial DNA. This case of mitochondrial cardiomyopathy demonstrated a low uptake of 123I-BMIPP, while the ...

Journal: :Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1997
T Kudoh N Tamaki Y Magata J Konishi R Nohara A Iwasaki S Ono Y Ohtake H Sugihara K Kuze Y Tsujimura T Miyazaki

UNLABELLED Iodine-123-BMIPP is an iodinated methyl-branched-chain fatty acid. Low uptake of BMIPP relative to thallium or other perfusion tracer indicates metabolically damaged but viable myocardium (for example, ischemic but viable myocardium). In some cases, however, negative myocardial uptake of BMIPP is observed. The main purposes of this study were to assess the frequency of such BMIPP fin...

Journal: :Kaku igaku. The Japanese journal of nuclear medicine 1999
N Isobe T Toyama H Hoshizaki S Oshima K Taniguchi T Iizuka N Kanazawa S Wakamatsu H Arisaka T Suzuki R Nagai T Inoue K Endo

We evaluated the characteristics of myocardial fatty acid metabolism in patients with left ventricular hypertrophy (LVH). Myocardial imaging with 123I-beta-methyl iodophenyl pentadecanoic acid (BMIPP) was performed in 28 patients with hypertrophic cardiomyopathy (HCM), 15 patients with hypertensive heart disease (HHD), 13 patients with aortic stenosis (AS) and 8 normal controls (NC). The patien...

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