نتایج جستجو برای: BHBA

تعداد نتایج: 206  

Journal: :Journal of dairy science 2009
M Iwersen U Falkenberg R Voigtsberger D Forderung W Heuwieser

The objective of this study was to determine the diagnostic performance of an electronic beta-hydroxybutyrate (BHBA) hand-held meter (Precision Xtra) for use in dairy cattle. Specific objectives were to compare the electronic BHBA meter with serum BHBA concentrations determined photometrically and 2 commonly used chemical cowside tests (Ketostix, Ketolac) and to evaluate accuracy in a field stu...

Journal: :Journal of dairy science 2007
A P W de Roos H J C M van den Bijgaart J Hørlyk G de Jong

Subclinical ketosis is a metabolic disorder in high-producing dairy cattle that can be detected by ketone bodies in milk: acetone (Ac), acetoacetate (AcAc), and beta-hydroxybutyrate (BHBA). Fourier transform infrared (FTIR) spectrometry is to a growing extent used for determination of milk constituents in milk recording, but as yet there is no calibration for ketone bodies available. The object...

Journal: :Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2015
Min Zhang Shiqi Zhang Qi Hui Lin Lei Xiliang Du Wenwen Gao Renhe Zhang Guowen Liu Xiaobing Li Xinwei Li

BACKGROUND/AIMS In dairy cows, β-hydroxybutyrate (BHBA) is utilized as precursors of de novo synthesized fatty acids in mammary gland. Ketotic cows are characterized by excessive negative energy balance (NEB), which can further increase the blood BHBA concentration. Sterol regulatory element-binding protein1 (SREBP1) and cell death-inducing DNA fragmentation factor-alpha-like effector α (Cidea)...

Journal: :Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2014
Xiaoxia Shi Xinwei Li Dangdang Li Yu Li Yuxiang Song Qinghua Deng Jianguo Wang Yuhang Zhang Hongyan Ding Liheng Yin Yuming Zhang Zhe Wang Xiaobing Li Guowen Liu

BACKGROUND/AIMS β-hydroxybutyrate (BHBA) is the major component of ketone bodies in ketosis. Dairy cows with ketosis often undergo oxidative stress. BHBA is related to the inflammation involved in other diseases of dairy cattle. However, whether BHBA can induce inflammatory injury in dairy cow hepatocytes and the potential mechanism of this induction are not clear. The NF-κB pathway plays a vit...

Journal: :Journal of dairy science 2014
J Denis-Robichaud J Dubuc D Lefebvre L DesCôteaux

The objectives of this study were (1) to determine the correlations between blood β-hydroxybutyrate (BHBA) and milk components [BHBA, acetone, fat, protein, and fat:protein (F:P) ratio], and (2) to establish optimal thresholds for milk components to predict hyperketonemia in dairy cows. Data on 163 cows from 37 herds were used in this cross-sectional study. Herds were visited once during the st...

Journal: :Journal of dairy science 2014
M Zarrin O Wellnitz H A van Dorland J J Gross R M Bruckmaier

Hyperketonemia interferes with the metabolic regulation in dairy cows. It is assumed that metabolic and endocrine changes during hyperketonemia also affect metabolic adaptations during inflammatory processes. We therefore studied systemic and local intramammary effects of elevated plasma β-hydroxybutyrate (BHBA) before and during the response to an intramammary lipopolysaccharide (LPS) challeng...

Journal: :Antioxidants & redox signaling 2015
Tao Shen Tao Jiang Min Long Jun Chen Dong-Mei Ren Pak Kin Wong Eli Chapman Bo Zhou Donna D Zhang

AIMS Lung cancer has a high worldwide morbidity and mortality. The employment of chemopreventive agents is effective to reduce lung cancer. Nuclear factor erythroid 2-related factor 2 (Nrf2) mitigates insults from both exogenous and endogenous sources and thus has been verified as a target for chemoprevention. Curcumin has long been recognized as a chemopreventive agent, but poor bioavailabilit...

2015
Shou-Peng Fu Wei Wang Bing-Run Liu Huan-Min Yang Hong Ji Zhan-Qing Yang Bin Guo Ju-Xiong Liu Jian-Fa Wang

β-hydroxybutyric acid (BHBA) regulates the synthesis and secretion of growth hormone (GH) and prolactin (PRL), but its mechanism is unknown. In this study, we detected the effects of BHBA on the activities of G protein signaling pathways, AMPK-α activity, GH, and PRL gene transcription, and GH and PRL secretion in dairy cow anterior pituitary cells (DCAPCs). The results showed that BHBA decreas...

2014
Shou-Peng Fu Su-Nan Li Jian-Fa Wang Yang Li Shan-Shan Xie Wen-Jing Xue Hong-Mei Liu Bing-Xu Huang Qing-Kang Lv Lian-Cheng Lei Guo-Wen Liu Wei Wang Ju-Xiong Liu

β-Hydroxybutyric acid (BHBA) has neuroprotective effects, but the underlying molecular mechanisms are unclear. Microglial activation plays an important role in neurodegenerative diseases by producing several proinflammatory enzymes and proinflammatory cytokines. The current study investigates the potential mechanisms whereby BHBA affects the expression of potentially proinflammatory proteins by...

Journal: :Research in veterinary science 2012
N Panousis Ch Brozos I Karagiannis N D Giadinis S Lafi M Kritsepi-Konstantinou

The accuracy of the Precision Xceed® hand-held meter as an on-site method for measuring blood β-hydroxybutyric acid (BHBA) and glucose concentrations, for the diagnosis of pregnancy toxemia and ketosis in dry and lactating dairy sheep, was assessed. Five to eight hours after the start of the morning feed, blood was collected once from 193 clinically healthy sheep (143 dry and 50 lactating). BHB...

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