نتایج جستجو برای: BCG vaccine
تعداد نتایج: 113591 فیلتر نتایج به سال:
Background: Thermal stability (TS) is a part of the BCG vaccine characterization by which the consistency of process in BCG vaccine production could be confirmed. To enhance the TS of the vaccine, some prevalent stabilizers in different concentrations were added to the final formulation of BCG bulk prior to Freeze-drying process. We found a formulation more effective than the current stabilizer...
Background: Although the efficacy of Bacillus Calmette-Guerin (BCG) vaccine in the prevention of tuberculosis has been noted consistently, the use of BCG vaccine is not without risk. In this study we aimed to evaluate immunologically, children with complication of BCG vaccination in North of Iran.Materials and Methods: This case-control study began in 30 Jan 2013 and was completed in 2 Jul 2015...
Background: Despite advances in the vaccinology and chemotherapy in the past century, tuberculosis is still responsible for two million deaths every year. Emergence of multi-drug resistant strain and coinfection of TB-HIV make it a serious concern. Treatment and control of tuberculosis is a great health burden in every community. Active tuberculosis in children has very severe consequences espe...
background: although the efficacy of bacillus calmette-guerin (bcg) vaccine in the prevention of tuberculosis has been noted consistently, the use of bcg vaccine is not without risk. in this study we aimed to evaluate immunologically, children with complication of bcg vaccination in north of iran.materials and methods: this case-control study began in 30 jan 2013 and was completed in 2 jul 2015...
context tuberculosis (tb) disease caused by mycobacterium tuberculosis (mtb) remains as one of the leading infectious causes of death and disease throughout the world. the history of tuberculosis as a worldwide fatal illness traces back to antiquity, being a well-known disease in ancient civilizations. evidence acquisition presented here, is a brief review of the history of tuberculosis and bac...
Background and Aim: In Iran vaccination with Bacillus Calmette-Guérin (BCG) is performed on all newborns within the first days of life for prevention of tuberculosis. It is a live attenuated vaccine and produced from genetically different vaccine strains of Mycobacterium bovis. This vaccine is safe but local adverse reactions such as administration site abscess and lymphadenitis occur in some h...
BCG vaccine has been used since 1921 for primary prevention of tuberculosis in man. The immunogenic efficacy of this vaccine has been reported between 2 to 83/. in various studies. In order to assess the efficacy of neonatal BCG vaccination in 200 infants who had received BCG vecctne at birth, BCG vaccine scars were measured and PPD test (5 unit strength) was performed at 3 months of age. The s...
conclusions it has the potential to cause disseminated infection, and an increasing number of immunocompromised patients prone to disease and the suboptimal preventive potency of this vaccine suggest the need for a global attempt to review its benefits and disadvantages. results worldwide, a proportion of new cases with multidrug-resistant tb (mdr-tb) were reported at 3.5% in 2013 without a sig...
PURPOSE Bacillus Calmette-Guérin (BCG) vaccine has widely been used to immunize against tuberculosis, but its protective efficacy is variable in adult pulmonary tuberculosis, while it is not efficiently protective against progressive infection of virulent Mycobacterium tuberculosis strains. In this study, the protective effects of plasmid DNA vaccine constructs encoding IL-12 or IL-18 with the ...
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