Bile acid CoA:amino acid N-acyltransferase (BAAT) is the terminal enzyme in the synthesis of bile salts from cholesterol and catalyzes the conjugation of taurine or glycine to bile acid CoA thioesters to form bile acid N-acylamidates. BAAT has a dual localization to the cytosol and peroxisomes, possibly due to an inefficient carboxy-terminal peroxisomal targeting signal (PTS), -serine-glutamine...

UNLABELLED Bile acid-coenzyme A:amino acid N-acyltransferase (BAAT) is the sole enzyme responsible for conjugation of primary and secondary bile acids to taurine and glycine. Previous studies indicate a peroxisomal location of BAAT in peroxisomes with variable amounts up to 95% detected in cytosolic fractions. The absence or presence of a cytosolic pool of BAAT has important implications for th...

Many authors have shown the potential mass savings that a ballute can offer for both aerocapture and entry. This mass savings could enhance or even enable many scientific and human exploration missions. Prior to flight of a ballute several technical issues need to be addressed, including aeroelastic behavior. This paper begins to address the issue of aeroelastic behavior by developing and valid...

BACKGROUND Intimate partner violence (IPV) is a human rights violation that is pervasive worldwide, and is particularly critical for women during the reproductive period. IPV includes physical, sexual and emotional abuse. Nurses on in-patient postpartum units are well-positioned to screen women for IPV, yet low screening rates suggest that barriers to screening exist. The purpose of this study ...

OBJECTIVE Insulin resistance contributes to the pathogenesis of both polycystic ovary syndrome (PCOS) and non-alcoholic fatty liver disease (NAFLD). The main aim of the present study was the evaluation of non-invasive indices of hepatic steatosis and fibrosis in PCOS women with or without metabolic syndrome (MetS). DESIGN In this cross-sectional study, three non-invasive indices for hepatic s...

The declining area and production of millets needed a national-level social influencer, Mann Ki Baat hosted by the Hon’ble Prime Minister was timely. present study tried to assess perception millet farmers, as how influencing event, such Baat, has impacted farming context. carried out in 68 districts belonging 28 states Union Territories with participation 1236 professionals from Krishi Vigyan ...

Background: The present research gives insights about Textual Data analytics of “Mann Ki Baat” – a monthly radio programme hosted by Shri. Narendra Modi, the Prime Minister India on All Radio. Using techniques textual data analytics, an analytical framework is designed in this paper. Methods: outline applied to corpus twelve (12) episodes Mann Baat 2.0 (March 2020 February 2021, after nationwid...

Depression is a complex disease characterized by a series of pathological changes. Research on depression is mainly focused on the changes in brain, but not on liver. Therefore, we initially explored the metabolic profiles of hepatic extracts from rats treated with chronic unpredictive mild stress (CUMS) by UPLC-Q-TOF/MS. Using multivariate statistical analysis, a total of 26 altered metabolite...