Lymphomas are solid tumors of immune system and Non-Hodgkin Lymphomas (NHL) is the most prevalent lymphomas; with wide ranges of histological and clinical features, it is so difficult to identify them. Herein, various bioinformatics tools (such as gene differential expressions, epigenetics and protein analysis) employed to find new treatment approach for NHL based on gene expression variation b...

Transforming growth factor beta (TGF-b) is a mediator released by nearly all cell types. It has suppression activity on the immune system, but exactly how this effect is carried out is not clear. Previous experiments showed that IgG interacts with or carriers active TGF-b, that could suppresses cytotoxic T-cell responses to an immunogenic tumor in mice. Since T cell receptor (TCR) has structura...

lymphomas are solid tumors of immune system and non-hodgkin lymphomas (nhl) is the most prevalent lymphomas; with wide ranges of histological and clinical features, it is so difficult to identify them. herein, various bioinformatics tools (such as gene differential expressions, epigenetics and protein analysis) employed to find new treatment approach for nhl based on gene expression variation b...

objectives: platelets are anucleated fragments derived from megakaryocytes. it has been demonstrated that platelets play a role in hemostasis and innate immunity. in addition, platelets have a cd40 ligand which is an important molecular marker in motivating immune cells. thus, platelets also have a role in adaptive immunity as seen by their ability to activate b cells. since human platelet micr...