introduction: this review reports the current results of hematopoietic stem cell transplantation (hsct) in patients who had received transplantation in the hematology-oncology and sct research center, tehran, iran. methods: in iran, from 1991 through 2010, a total of 3170 hematopoietic stem cell transplantation have been carried out. the male/female patient ratio was 1909/1261 with a median age...

introductio: hematopoietic stem cell transplants (hsct) are considered as treatment options for patients with solid tumors. transplant numbers have changed significantly over the last decade. we have done autologous and allogeneic hsct for treatment of solid tumor patients in our center. methods: in order to show the transplant effect on solid tumor treatment, we collected data from 71 patients...

Background: Burkitt lymphoma is a common subtype of non-Hodgkin lymphoma in children. It has a rapid and aggressive clinical course with frequent involvement of bone marrow and central nervous system. Systemic chemotherapy is the mainstay of the treatment for this malignancy in children. In this systematic review, we discuss autologous and allogeneic hematopoietic stem cell transplantation (HSC...

background: segmental vitiligo is a small subset albeit persistent form of focal vitiligo with dermatomal distribution and resistant to medical therapy. in recent years, surgical therapy as hair follicle autograft transplantation has been a hot topic in management of segmental vitiligo. in this study, we evaluated the efficacy of this method in segmental vitiligo lesions. methods: the study rec...

objectives: gingival recession can lead to root exposure and discomfort for patients. there are various techniques for root coverage. the aim of this study was to compare the use of gingival unit graft (palatal graft including the marginal gingiva and papillae) with free gingival graft for treatment of localized gingival recession. materials and methods: in this randomized controlled clinical t...

objective(s) articular cartilage tissue defects cannot be repaired by the proliferation of resident chondrocytes. autologous chondrocyte transplantation (act) is a relatively new therapeutic approach to cover full thickness articular cartilage defects by in vitro grown chondrocytes from the joint of a patient. therefore, we investigated the redifferentiation capability of human chondrocytes mai...

background: the aim of the present clinical trial was to investigate the efficacy of autologous bone marrow mesenchymal stem cells (bm-mscs) in glycemic control of diabetic patients without using any immunosuppressive drugs over a nine-month period. method: twenty-three patients with t1dm, at 5 to 30 years of age and in both sexes, participated in this study. this trial consisted of two phases;...

Six patients with disseminated Hodgkin's disease resistant to MOPP (mechlorethamine, vincristine, procarbazine and prednisolone), and ABVD (adriamycin, bleomycin, vinblastine and dacarbazine) chemotherapy were treated with high-dose chemotherapy and autologous marrow transplantation. The patients first underwent marrow aspiration and storage for subsequent autologous bone marrow transplant...