نتایج جستجو برای: Auger therapy
تعداد نتایج: 658328 فیلتر نتایج به سال:
introduction: auger electron based radioimmunotherapy (rit) using 111in-dota-trastuzumab (111in-dota-antiher2) feasibility was studied in vitro on a her2/neu positive cell line, skbr3. methods:111in-dota-antiher2 was prepared according to the optimized conditions followed by quality control tests including radiochemical purity; immunoreactivity). skbr3 as a her2/neu positive cell line was used ...
Auger electrons and characteristic X–rays, collectively named as atomic radiation, are emitted following atomic ionization. Radionuclides that emit Auger electrons have been of particular interest as therapeutic agents. This is primarily due to its short range in tissue, controlled linear paths, and high linear energy transfer of these particles. Their biological effects are very localized thus...
Auger electrons and characteristic X-rays, collectively named as atomic radiation, are emitted following atomic ionization. Radioisotopes that emit Auger electrons have been of particular interest as therapeutic agents. This is primarily due to its short range in tissue, controlled linear paths and high linear energy transfer of these particles. Their biological effect is very localised thus ma...
Glioblastoma, the most common and malignant primary brain tumor, always recurs after standard treatment. Therefore, promising new therapeutic approaches are needed. Short-range Auger-electron-emitters carry the ability of causing highly damaging radiation effects in cells. The aim of this study was to test the effect of [125I]5-Iodo-2'-deoxyuridine (125I-UdR, a radioactive Auger-electron-emitti...
anxiety is one common disorder during childhood. in curing anxiety disorders, there are different types of psychological remedies, pharmotherapy, family therapy, and music therapy that can improve the individual’s anxiety, but we need some other remedies to improve social and emotional relationship and interactions. considering the importance of curing the anxiety disorders, the effect of sand ...
Introduction: Theranostics, in particular, the use of radionuclides with the capability of simultaneous imaging and treatment has opened new horizons in personalized treatment planning of targeted radiation therapy. In this approach, positive beta or gamma emitters are required for imaging and alpha, beta and Auger electrons for treatment purpose. On the other hand, studies hav...
Auger electron emitting radionuclides in cancer therapy offer the opportunity to deliver a high radiation dose to the tumor cells with high radiotoxicity while minimizing toxicity to normal tissue. We have in this study identified the Auger emitter Sb119 as a potent nuclide for targeted radionuclide therapy based on theoretical dosimetry calculations at a subcellular scale. From these calculati...
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