we compared the extent of temporary threshold shift (tts) and hair cell loss following high level 4 khz noise exposure with those preconditioned with moderate level 1 and 4 khz octave band noise. fifteen male albino guinea pigs (300- 350 g in weight) were randomly allocated into three groups: those exposed to 4 khz octave band noise at 102 db spl (group 1, n=5); those conditioned with 1 khz oct...

objective(s): noise-induced hearing loss (nihl) is the major cause of acquired hearing loss.  celecoxib, a cyclooxygenase-2 (cox-2) inhibitor, is a non- steroidal anti- inflammatory drug (nsaid) with known antioxidant and antineoplastic activity. therefore, we monitored the extent of temporary noise- induced threshold shifts (tts) and cochlear damage caused by high level 4- khz noise exposure t...

noise induced hearing loss (nihl) is one of the most important occupational disease worldwide. nihl has been found potentiate by simultaneous carbon monoxide (co) exposure. free radicals have been implicated in cochlear damage resulted from the exposure to noise and due to the co hypoxia. this study examined whether α-tocopherol administration, as a free radical scavenger, causes the attenuatio...

background and aims: this is a pilot study investigated the prevalence of hearing impairment and the impact of the known risk factors for hearing loss on infants at risk born in kuwait. methods: two hundred infants with risk of hearing impairment who met the joint committee on infants hearing (1990) criteria were screened. all newborns were included in this study if they had hospital stay for m...

multiple sclerosis (ms) is a demyelinating disorder of central nervous system. it involves 8th cranial nerve and its central nuclei and is an uncommon cause of the sensorineural hearing loss. for determining the prevalence of hearing loss (hl) especially retrocochlear type in ms, a cross-sectional study was designed using pure-tone audiometry (pta), otoacustic emissions (oaes), auditory brainst...

abstract:background : hyperbilirubinemia is one of the most common cause of congenital sensory neuronal hearing loss. these patients are screened by auditory brainstem response (abr) test at bilirubin levels higher than 1% of gestational weight. aim: to determine whether hyperbilirubinemia less than 1% of gestational weight could induce hearing loss and abnormal auditory brainstem response (abr...

Gap detection is a commonly used measure of temporal resolution, although the mechanisms underlying gap detection are not well understood. To the extent that gap detection depends on processes within, or peripheral to, the auditory brainstem, one would predict that a measure of gap threshold based on the auditory brainstem response (ABR) would be similar to the psychophysical gap detection thre...

Elderly people often show degraded hearing performance and have difficulties in understanding speech, particularly in noisy environments. Although loss in peripheral hearing sensitivity is an important factor in explaining these low performances, central alterations also have an impact but their exact contributions remained unclear. In this study, we focus on the functional effects of aging on ...

regardless of severity, earlier intervention to correct hearing loss in children improves speech development and conversational abilities. a cross-sectional study was performed on 230 neonates who were at risk of hearing loss in tehran university of medical sciences hospitals between september 2000 and february 2002. hearing was examined before the 3rd month by auditory brainstem responses (abr...

Background: Occupational noise-induced hearing loss (ONIHL) is a hearing disorder that affects workers all over the world. Preconditioning with several mild or less potent stressors will effectively prevent the development of noise-induced hearing loss. This study investigated the possible preventive effects of normobaric hyperoxia preconditioning on preventing the noise-induced hearing impairm...