introduction:yasthenia gravis is an autoimmune disorder resulting from a decreased number of active acetylcholine receptors at the neuromuscular junction. thymectomy is one of its current treatments. due to sensitivity of myasthenic patients to non-depolarizing muscle relaxants and also the interaction of this medication with anti-cholinestrase drugs, determining the dosage of non-depolarizing ...

BACKGROUND The most sensitive diagnostic criterion of myasthenia gravis is a decrement in the muscular response to repetitive stimulation. The authors hypothesized that myasthenia gravis patients who show a train-of-four ratio (T4/T1) < 0.9 in the preanesthetic period will have increased sensitivity to nondepolarizing neuromuscular blocking agents compared with myasthenia gravis patients with p...

The degree, duration of and recovery from neuromuscular blockade induced by atracurium in a patient with myasthenia gravis were monitored and recorded using the evoked compound muscle action potentials (EMG). The anaesthetic and perioperative management were simplified by the use of this technique. The significance of the behaviour of atracurium is discussed.

Introduction:yasthenia gravis is an autoimmune disorder resulting from a decreased number of active acetylcholine receptors at the neuromuscular junction. Thymectomy is one of its current treatments. Due to sensitivity of myasthenic patients to non-depolarizing muscle relaxants and also the interaction of this medication with anti-cholinestrase drugs, determining the dosage of non-depolarizing ...

Objective: General anesthesia requires smooth endotracheal intubation, aided by neuromuscular blocking agents. Atracurium and cis-atracurium are non-depolarizing agents used for muscle relaxation. Succinylcholine, though effective, has undesirable side effects. This study aims to compare atracurium different doses of assess their onset, duration, recovery, hemodynamic effects, in order identify...

BACKGROUND Rocuronium and atracurium are muscle relaxants used for short-and intermediate-duration surgical procedures. This study compares rocuronium and atracurium with regard to neuromuscular efficacy, hemodynamic changes, and their effects on plasma histamine concentration. MATERIALS AND METHODS Sixty adult patients scheduled for general surgical operations lasting less than 120 minutes w...