background: androgen receptors (ar) play an important role in proliferation of cancerous prostatic cells and prevention of apoptotic signaling. current drugs cannot inhibit the activity of these receptors very well. establishment of appropriate animal models is essential for discovery of new drugs of target therapy in hormone dependent prostate cancer. materials and methods: standard prostatic ...

the ability to maintain and study human tissues in in-vivo environment has proved to be a valuable tool in breast cancer research for several decades. the most widely tissues have been xenografts established human breast cancer cell lines into athymic nude mice. the aim of this study was to provide a new accurate and affordable method for the establishment of breast cancer xenograftin nude mice...

The ability to maintain and study human tissues in in-vivo environment has proved to be a valuable tool in breast cancer research for several decades. The most widely tissues have been xenografts established human breast cancer cell lines into athymic nude mice. The aim of this study was to provide a new accurate and affordable method for the establishment of breast cancer xenograftin nude mice...

Cellular hair growth therapy is an emerging approach to alopecia. Recently, Tsuboi et al. (J Am Acad Dermatol. 2020;83,109–116.) have observed hair-growth stimulation by dermal-sheath-cup cells in patients with androgenic Hair follicle-associated pluripotent (HAP) stem cells, originate the bulge area and express nestin, been shown differentiate multiple cell types including keratinocytes, neuro...

are data to suggest it is immunological. Prehn and Outzen (14) showed that syngeneic tumors of high immunogenicity grew better in irradiated adult or untreated newborn athymic mice than in control adult athymic mice. These authors suggested growth of immunogenic tumors in nude mice may be due to an overloading of a weak immune system. No evidence of immu nological memory to the tumor antigen co...

Athymic BALB/c nude mice and euthymic BALB/c mice were infected with Rickettsia akari by the intraperitoneal route. The rickettsialpox infection was terminated in euthymic mice with only two intraperitoneal injections of the antibiotic oxytetracycline, whereas prolonged treatment was necessary to terminate the infection in athymic mice. Both athymic and euthymic mice produced specific antibody,...