the role of chlamydia pneumoniae in asthma has drawn much attention in recent years. in this study we assessed the prevalence of c. pneumoniae infections in patients with chronic stable and acute exacerbation of asthma and compared it with normal population. twenty adult patients with chronic stable asthma and 21 patients with acute exacerbations of asthma and 41 matched control subjects were s...

  Background and Objectives: Apoptosis of eosinophils is of significant value in assessing the airway inflammation in patients with asthma. Our purpose was to investigate the degree of expression of the Bcl-2 protein in sputum eosinophils during acute asthma exacerbation and its relationship with exacerbation severity.    Materials and Methods: The study was carried out in Mostafa Khomeini Ho...

introduction:  asthma exacerbation is common in children. treatment with oral corticosteroids (ocs) and inhaled corticosteroids are suggested for asthma exacerbation. it is shown that inhaled corticosteroids has similar outcome in reducing asthma symptoms compared to ocs. but few studies have evaluated the pulmonary function changes in these two treatments. in this study, we evaluated the chang...

the purpose of this study was to determine the clinical significance of changes in the plasma  adiponectin  concentration  in  patients  with  bronchial  asthma  and  to  test  the association between the single nucleotide polymorphisms (snps) rs2241766 and rs1501299 in the adipoq gene and bronchial asthma in the chinese li population.we selected 120 cases and 120 controls, and plasma adiponect...

ykl-40 (chitinase-3-like-1) has been introduced as a marker of inflammation in asthma. the aim of this study was to determine the role of ykl-40 in asthma and to evaluate the relationship between ykl-40 and asthma severity. in the study, 60 non-smoker asthma patients without additional diseases (aged between 20-60 years, female: 34) were grouped [group i: well controlled asthma patients (n: 30)...

Introduction:  Asthma exacerbation is common in children. Treatment with oral corticosteroids (OCS) and inhaled corticosteroids are suggested for asthma exacerbation. It is shown that inhaled corticosteroids has similar outcome in reducing asthma symptoms compared to OCS. But few studies have evaluated the pulmonary function changes in these two treatments. In this study, we evaluated the chang...

background and objectives: apoptosis of eosinophils is of significant value in assessing the airway inflammation in patients with asthma. our purpose was to investigate the degree of expression of the bcl-2 protein in sputum eosinophils during acute asthma exacerbation and its relationship with exacerbation severity.    materials and methods: the study was carried out in mostafa khomeini hospit...

airway mucus hypersecretion and increased oxidative stress are clinical and pathophysiological features of asthma exacerbation. we studied effects of n-acetylcysteine (nac) as a mucolytic and antioxidant agent in asthma exacerbation. in this randomized, single-blinded, placebo-controlled study 50 patients ( 17 male, 33 female, mean age 48.94±13.68) with asthma exacerbation were randomized to re...