introduction: membrane cofactor protein (mcp or cd46) is one of the regulatory of complement system. it is present in all somatic cells except in rbc. it is also present in all body fluids and semen. the aim of this study was measuring the concentration of this protein in semen of fertile and infertile individuals and to study the relationship between the concentration of this protein and semen...

Recent studies have shown Y chromosome microdeletions associated with male infertility. The factors responsible for Y chromosome microdeletions in spermatozoa remain unresolved. However, the environmental pollutants are known to damage DNA in differentiating and maturing germ cells in the male reproductive tract. Therefore, the aim of this study was to investigate the effects of seminal hexachl...

Background: Lipid peroxidation is known to cause various impairments to sperm cells and may play a major role in the etiology of male infertility. Asthenospermia is the main factor of male infertility and has significantly higher level of peroxidation than in normozoospermic males. Materials and Methods: Using thiobarbituric acid (TBA) assay procedure, we have determined the level of lipid pero...

Background s:648:"The infertility has recently been estimated to affect approximately 9% of couples worldwide. Androgens and a functional androgen receptor (AR) are essential for normal development of the male gender, and for maintenance of spermatogenesis throughout the life. Two polymorphic trinucleotide repeats, CAG and GGN, encoding for the amino acids glutamine and glycine, respectively ar...

Results: Compared with the other groups, oligospermic group had the highest proportion of specimens with abnormal liquefaction (26.0%) and leukocyte counts (32.0%). Both oligospermic and asthenospermic groups had comparable sperm motility, which was lower than that in normospermia (p < 0.05). The mean levels of γ-GT and Mg in oligospermia were significantly lower than that in all other groups. ...

Background: The Y chromosome microdeletion is one of the best-documented causes of male infertility but the factors responsible for Y chromosome microdeletions in spermatozoa remain unresolved. However, the environmental pollutants are known to damage DNA in differentiating and maturing germ cells in the male reproductive tract. In view of this, the objective of the present study was to explore...

background: lipid peroxidation is known to cause various impairments to sperm cells and may play a major role in the etiology of male infertility. asthenospermia is the main factor of male infertility and has significantly higher level of peroxidation than in normozoospermic males. materials and methods: using thiobarbituric acid (tba) assay procedure, we have determined the level of lipid pero...