a 46- year–old man with pulmonary tuberculosis which had treated with ant tuberculosis drugs was referred to medical mycology laboratory, school of public health and institute of public health research for coughing and bloody sputum. chest x-ray revealed a cavern with a moveable mass in right apical lobe. direct examination of sputum showed wide septated dichotomous hyphae and aspergillus fumig...

background vancomycin-resistant enterococci (vre) are the most common nosocomial pathogen worldwide. colonization with vre can lead to serious infection, some of which e.g. vre sepsis can be fatal. because vre are dangerous important pathogens, we aimed to determine the prevalence of vre among patients admitted in infectious, icu and surgery wards in a referral teaching hospital in isfahan, ira...

While the epidemiology and clinical differences of various Candida spp. has been relatively well-identified, data regarding invasive aspergillosis (IA) caused by different Aspergillus spp. are insufficient.We aimed to determine the epidemiology of culture-positive invasive pulmonary aspergillosis (IPA) and to compare the characteristics and outcomes of Aspergillus fumigatus IPA with those of no...

aspergillus fumigatus is a saprophyte fungus, widely spread in a variety of ecologicalniches and the most prevalent aspergilli responsible for human and animal invasiveaspergillosis. the first step to develop novel and efficient therapies is the identificationand understanding of the key tolerance and virulence factors of pathogens. the mainfocus of the present study is to perform the similarit...

We sought to determine if sufficient redundancy exists between specific IgE testing for Aspergillus fumigatus and Aspergillus niger to eliminate one of the assays in determining Aspergillus hypersensitivity. We reviewed regional laboratory results comparing A fumigatus-specific IgE with A niger-specific IgE using the Pharmacia UniCAP system (Pharmacia, Kalamazoo, MI). By using the Fisher exact ...

background & aim: in recent years using from plant product has been considered wildly as main factor for preventing pathogenic diseases cassed by attacking viruses, bacteria, fungi and parasites. there are some funguses which could be the factors for affliction of some diseases in human, plants and animals. plant extracts are those which could act and be used as preventing from these diseas...

silymarin, the principal constituent of silybum marianum, is one of the most commonlyused herbal therapies as a natural antioxidant, hepatoprotector and antihepatotoxic agent,in counteracting the toxic effects of mycotoxins. to determine the efficacy of silymarin,the levels of hematological and serum biochemical parameters of 70 ross broilers from35 to 49 days of age in an experimental chronic ...

The MICs of amphotericin B and itraconazole for 230 isolates of Aspergillus spp., comprising 156 Aspergillus fumigatus, 20 Aspergillus terreus, 22 Aspergillus flavus, 17 Aspergillus nidulans and 15 Aspergillus niger, were determined by a broth microdilution method with RPMI 1640 medium. No isolate was detected with an MIC of amphotericin B >2 mg/L. Itraconazole MICs >16 mg/L were detected for f...

Invasive aspergillosis is a leading cause of infectious death in immunosuppressed patients. Here, we adapted a phage display library-based selection to screen and identify binding peptides to the surface of Aspergillus fumigatus conidia and hyphae. We identified a peptide (sequence CGGRLGPFC) that reliably binds to the surface of Aspergillus fumigatus hyphae. Binding was not Aspergillus strain ...