OBJECTIVES Artemisia is a genus of herbs and small shrubs forms an important part of natural vegetation in Iran. It has been reported that several Artemisia species possess anti-proliferative effects. Considering the value of this genus in anti-cancer researches we have chosen Artemisia biennis for cytotoxic and mechanistic studies. MATERIALS AND METHODS In this study we have investigated the...

the formation of hemozoin (malaria pigment) has been proposed as an ideal drug target for antimalarial screening programs. in this study, we used an improved, cost-effective and high-throughput spectrophotometric assay to screen plant extracts for finding novel antimalarial plant sources. fifteen extracts with different polarity from three iranian artemisia species, a. ciniformis, a. biennis an...

Objective. Artemisia ciniformis (Asteraceae) and A. biennis are two of 34 Artemisia species growing naturally in Iran. In this study we investigated whether different extracts of A. ciniformis and A. biennis have protective effect against hydrogen peroxide-induced cytotoxicity in rat cardiomyoblast cells (H9c2). Method. The dried and ground aerial parts of these two species were extracted succe...

OBJECTIVES This study was designed to indicate whether different fractions from Artemisia biennis hydroethanolic extract could provide cytoprotection against oxidative stress and apoptosis induced by doxorubicin (DOX) in rat pheochromocytoma cell line (PC12). MATERIAL AND METHODS Cell viability was determined by MTT assay. Also, activation of caspase-3 and superoxide dismutase were evaluated ...

total phenolic contents (tpc) of five different extracts (petroleum ether, dichloromethane, ethyl acetate, ethanol and ethanol-water) of artemisia biennis willd were measured in this work. the antioxidant activity was investigated by three different methods: β-carotene bleaching (bcb) test, 2,2-diphenyl-1-picrylhydrazyl (dpph) radical scavenging method and ferrous ion chelating (fic) assay. amo...

objective(s): artemisia is a genus of herbs and small shrubs forms an important part of natural vegetation in iran. it has been reported that several artemisia species possess anti-proliferative effects. considering the value of this genus in anti-cancer researches we have chosen artemisia biennis for cytotoxic and mechanistic studies. materials and methods:in this study we have investigated th...

The formation of hemozoin (malaria pigment) has been proposed as an ideal drug target for antimalarial screening programs. In this study, we used an improved, cost-effective and high-throughput spectrophotometric assay to screen plant extracts for finding novel antimalarial plant sources. Fifteen extracts with different polarity from three Iranian Artemisia species, A. ciniformis, A. biennis an...

objective(s): this study was designed to indicate whether different fractions from artemisia biennis hydroethanolic extract could provide cytoprotection against oxidative stress and apoptosis induced by doxorubicin (dox) in rat pheochromocytoma cell line (pc12). material and methods:cell viability was determined by mtt assay. also, activation of caspase-3 and superoxide dismutase were evaluated...