PURPOSE The aim of this study was to characterize the arylsulfatase I (ARSI) gene that has been shown to be preferentially expressed in the human retinal pigment epithelium cell line ARPE-19 and to propose it as a candidate gene responsible for inherited eye diseases such as retinitis pigmentosa (RP). METHODS Full-length cDNA clones encoding ARSI, arylsulfatase A (ARSA), and sulfatase modifyi...

Insulators are genomic elements that regulate transcriptional activity by forming chromatin boundaries. Various DNA insulators have been identified or are postulated in many organisms, and the paradigmatic CTCF-dependent insulators are perhaps the best understood and most widespread in function. The diversity of DNA insulators is, however, understudied, especially in the context of embryonic de...

Large Scale Demonstration (LSD) of Malt barley were conducted in Oromia regional state two producing Zones Arsi. From the zones (Arsi and west Arsi ) 4 districts three them namely Lemu-bilbilo, Arsi-Robe Hetosa from zone, one district Kofale West zone included program.

Multiple sulfatase genes have been reported on the human genome, including Arylsulfatase B (ARSB), Arylsulfatase I (ARSI) and Arylsulfatase J (ARSJ). ARSB is localized in lysosomes and catalyses the hydrolysis of chondroitin and dermatan sulfate groups. Bioinformatic analyses of vertebrate genomes were undertaken using known human ARSB, ARSI and ARSJ amino acid sequences to study the relatednes...

Abstract: The dead-time effect, as an intrinsic problem of the converters based on the half-bridge unit, leads to distortions in the converter output. Although several dead-time effect compensation or elimination methods have been proposed, they cannot fully remove the dead-time effect of blanking delay error, because the output current polarity is difficult detect accurately. This paper utiliz...

The intent of this study was to examine the leadership of technical and vocational education and training (TVET) reforms in Arsi administrative Zone of Oromia Region, Ethiopia. To achieve this purpose, researcher used mixed approach research paradigm. The participants of the study include: 45 trainers, 35 board members, and 18 District officials. Moreover, 6 Deans, 6 core process owners, 2 zona...

Silicon sputter yield under medium energy Ar+ ion bombardment is calculated via molecular dynamics, using a highly accurate interatomic potential for Ar–Si interactions derived from first-principles calculations. Unlike the widely used universal repulsive potentials such as the Moliere or ZBL parameterizations, this new potential, referred to as DFT-ArSi, is developed via localized basis densit...

Abstract: Attributing to the advantages of high efficiency, low electromagnetic interference (EMI) noise and closest to the pulse-width-modulation (PWM) converter counterpart, zero-voltage-transition (ZVT) PWM soft-switching inverters are very suitable for high-performance applications. However, the conventional control algorithms intended for high efficiency generally results in voltage distor...

Background In Ethiopia, one in 17 children dies before 1 year of age and one in 11 children dies before 5 years. Research that examines the factors influencing the implementation of the Integrated Management of Neonatal and Childhood Illnesses (IMNCI) strategy in Ethiopia is limited. This study aimed to identify the factors compelling the execution of IMNCI by nurses in four districts of West A...

the study was carried out at agarfa atvet college dairy farm to evaluate the reproductive performance of holstein friesian× arsi and holstein friesian ×boran cattle. for the study, records compiled from 1983 to 2012 at the agarfa dairy farm were used as original data. the effects of breed, bloodlines, season and parity on the reproductive traits were evaluated. data were analyzed using the gene...