this review provides the basic principle and rational for roc analysis of rating and continuous diagnostic test results versus a gold standard. derived indexes of accuracy, in particular area under the curve (auc) has a meaningful interpretation for disease classification from healthy subjects. the methods of estimate of auc and its testing in single diagnostic test and also comparative studies...

A full-vectorial finite-element-based approach has been developed to find accurate modal solutions of acoustic modes in Ge-doped planar silica waveguides. The structural symmetry is exploited, and Aitken's extrapolation is also used to improve the accuracy of the solution. The spatial dependences of the dominant and nondominant displacement vectors are shown for the fundamental and higher-order...

the absence of a universally accepted mathematical model for assessment of the effectiveness of drugs in the process of wound healing is one of the problems the health professionals have been faced. in this study, an “empirical” mathematical model is presented to evaluate its reliability from an experimental viewpoint and from a comparative aspect with previous models used to study wound healin...

two sensitive spectrophotometric methods are presented for the assay of repaglinide in bulkdrug and in formulations using methyl orange, as reagents. oxidant by reacting with a fixedamount of either methyl orange and measuring the absorbance at 485.2 nm (method-i) andmeasuring the absorbance at 618.9 nm (method-ii). developed method is based on the formationof extractable colored complex of dru...

diastolic phase of cardiac function is associated with lower arterial flow and hence higher concentration of intra arterially injected drug is achieved at the site of injection. it is herein postulated that drugs show higher efficacy when injected during the diastolic phase of cardiac function. it is also postulated that this benefit cannot be achieved when the drug is injected with higher rate...