نتایج جستجو برای: Apoptosis Related Genes

تعداد نتایج: 1644143  

Journal: :iranian biomedical journal 0
معصومه عبدالهی maasoume abdollahi مژده صالح نیا mojdeh salehnia ساغر صالح پور saghar salehpour نسیم قربانمهر nassim ghorbanmehr

background: in this study, we evaluated the incidence of apoptosis at the ultrastructural levels and expression of some apoptosis-related genes in vitrified human ovarian tissue just after warming. methods: human ovarian tissue biopsies from 23 women after caesarean section were transported to the laboratory within 2 hours, and then they were cut into small pieces. some pieces were vitrified an...

Maasoume Abdollahi, Mojdeh Salehnia, Nassim Ghorbanmehr, Saghar Salehpour,

Background: In this study, we evaluated the incidence of apoptosis at the ultrastructural levels and expression of some apoptosis-related genes in vitrified human ovarian tissue just after warming. Methods: Human ovarian tissue biopsies from 23 women after caesarean section were transported to the laboratory within 2 hours, and then they were cut into small pieces. Some pieces were vitrified an...

Background: Colorectal cancer (CRC) is attributed as one of the most common malignancies worldwide. CD133 molecule, as a pentaspan transmembrane glycoprotein, confers stem cell-related characteristics, including self-renewal and multi-directional differentiation capability. CD133 plays important roles in the progression of CRC by conferring apoptotic resistance and migration ab...

Abbas Ghotaslou, Amir Samii, Hassan Boustani, Minoo Shahidi, Omid Kiani Ghalesardi,

Background: Doxorubicin (DOX)-induced cardiotoxicity appears to be a growing concern for extensive use in acute lymphoblastic leukemia (ALL). The new combination treatment strategies, therefore might be an effective way of decreasing its side effects as well as improving efficacy. AMG232 (KRT-232) is a potential MDM-2 inhibitor, increasing available p53 through disturbing p53-MDM-2 interaction....

Journal: :international journal of preventive medicine 0
mehdi nikbakht dastjerdi ebrahim momeni mehdiabady farhad golshan iranpour hamid bahramian

background: nigella sativa has been a nutritional flavoring factor and natural treatment for many ailments for so many years in medical science. earlier studies have been reported that thymoquinone (tq), an active compound of its seed, contains anticancer properties. previous studies have shown that tq induces apoptosis in breast cancer cells but it is unclear the role of p53 in the apoptotic p...

Journal: :physiology and pharmacology 0
parva nasimi department of biology, fars science and research branch, islamic azad university, fars, iran mohammad reza tabandeh department of biochemistry and molecular biology, faculty of veterinary medicine, shahid chamran university of ahvaz, ahvaz, iran akbar vahdati department of biology, fars science and research branch, islamic azad university, fars, iran saeed khatamsaz department of biology, kazerun branch, islamic azad university, kazerun, iran

introduction: busulfan as a chemotherapeutic agent causes testicular germinal epithelium depletion and cytotoxicity in germ cells. the aim of this study was to assess antioxidant status, reactive oxygen species (ros) generation and apoptosis-related genetic markers of adult male mouse sperm following busulfan treatment. materials and methods: forty adult nmri mice (30 ± 5 g) were divided into t...

Introduction: The imbalance of the microbial ecosystem causes biological changes associated with colorectal cancer and cell proliferation and their planned death, as well as the immune responses. The aim of this study was to determine the effect of probiotic bacteria on the expression of genes associated with growth, metastasis and apoptosis in cancer cells of the HT29 colon.   Materials & Me...

Objective(s): The protozoan Toxoplasma gondii as an intracellular protozoan is widely prevalent in humans and animals. Infection generally occurs through consuming food contaminated with oocysts and tissue cysts from undercooked meat. The parasite is carried in sexual fluids like semen but there is little information about the effect of T. gondii on the male reproducti...

Journal: :Applied Nanoscience 2021

Mechanical stimulation is capable of affecting cell apoptosis. Several studies have shown that the Bcl-2 gene family, including and Bax gene, plays an important role in apoptosis, as proteins produced by can inhibit apoptosis while promote Understanding how mechanical alters expression apoptosis-related genes cardiomyocytes contribute to development ways cardiomyocyte necrosis. Intermediate myo...

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