objective: nano components are today’s new wonder material. however, the safety or toxicity of these components in humans is not yet clear. in a previous study we indicated that nano zno (nzno) has a stronger anxiolytic effect compared to the conventional zno (czno). the present study was designed to evaluate the intraperitoneal administration of an opioidergic receptor agonist and antagonist o...

introduction: anxiety is a generalized and extremely unpleasant feeling of vague dread of unknown origin which is accompanied by physical feelings like exhaustion, chest tightness, palpitations, sweating, headache, sudden desire to urinate, restlessness, and a desire to move. anxiety is one of the most common psychiatric disorders which lead to problems in many aspects of individual, family, an...

background. given the influence of systemic blood pressure on pulpal blood flow, anxiolytics prescribed may alter the pulpal blood flow along with the local anesthetic solution containing a vasoconstrictor. this study evaluated the impact of preoperative anxiolytics and vasoconstrictors in local anesthetic agents on pulpal oxygen saturation. methods. thirty anxious young healthy individuals wit...

putative activity of hydroalcoholic and aqueous infusion extracts of echium amoenum l. was investigated in mice using the rotarod model of motor coordination and the elevated plus maze model of anxiety. the extracts were administered intraperitonealy (i.p.) once, one hour before performing the tests. preliminary phytochemical study of the plant, with standard procedures, showed that it contains...

AIMS AND OBJECTIVES To examine the association of anxiety level and anxiolytic medication use with in-hospital complications in patients following acute myocardial infarction (AMI). BACKGROUND There are conflicting data about the protective effect of anxiolytic medication used in patients after acute myocardial infarction. Examination of the interaction of anxiolytic medication and anxiety le...

OBJECTIVE The aim of this study is to investigate the antidepressant and anxiolytic effects of simvastatin in rats. METHODS Sixty-four male adult (8-9 weeks old) Sprague-Dawley rats (200-250 g) were used. The forced swimming test and the elevated plus maze test were used for testing the antidepressant and anxiolytic effects. Eight groups were formed: control (saline), simvastatin 10, 30, and ...

the anxiolytic effect of the flower of echium. amoenum was shown in several experimental studies in mice. the present study was aimed to determine whether tolerance develops to anxiolytic action of e. amoenum in mice. nmri male mice were injected intraperitoneal with hydroalcoholic extract (12.5, 25 and 50 mg/kg) or saline once each day (8 am) for period of 7 days and then tested on light/dark ...

angiogenesis which is the recruitment of new blood vessels is a critical process in several chronic diseases and is an essential component of tumor or cancer progression. development of therapies aimed at inhibiting the angiogenesis, in combination with classical anti-cancer therapies, is among the most intensively studied approaches to treat the cancer. in this study the effect of chlordiazepo...

introduction: the mechanisms of hepatic encephalopathy are not fully understood. moreover, there is no comprehensive data concerning the effects of nitric oxide (no) system on anxiolytic-like behaviors induced by bile duct ligation (bdl). methods: male mice weighing 25-30 g were used and anxiety-like behaviors were tested using hole-board task. results: the data indicated that cholestasis incre...

STUDY AIMS 2(S)-neopincirin (NEO) is a constituent from of Clinopodium mexicanum, which is used in traditional Mexican herbal medicine for its tranquilizing and analgesic properties. This study investigated the anxiolytic-like, sedative and antinociceptive effects of NEO in several mice models. MATERIAL AND METHODS The anxiolytic-like effect was evaluated in the hole-board (HBT) and Open Fiel...