Background: Apium graveolens has been used in Unani system of medicine as anti inflammatory, uricosuric, diuretic, carminative, antidyslipidemic, abdominal discomfort etc.The aim of the present study was to determine the antispasmodic activity of A. graveolens in Guinea Pigs against histamine induced contractions. Materials and Methods: Antispasmodic activity of PEESAG at the doses of 100, 200,...

The crude native oil and purified seed oil of Mesua ferrea were studied for their effect on isolated rat il eum by taking standard spasmodic and antispasmodic drugs. The crude oil of seed showed significant antispasmodic activity but purified oil was devoid of any antispasmodic activity.

Background: Apium graveolens Linn. is one of the oldest medicinal plants which used since ancient time in Unani System of Medicine for the disease of gastrointestinal tract which acts as antispasmodic and carminative activity. The aim of this study was to determine the antispasmodic activity of A. graveolens in Guinea Pigs Ileum against acetylcholine induced contractions. Materials and Methods:...

According to ayurvedic texts shodhan vidhi is an important process which enhances the biological activity of a compound and reduces the toxicity at the same time. Before incorporating into formulations, guggul is processed using Shodhan vidhi involving different shodhan dravyas like gulvel, gomutra, triphala, dashmul. We have evaluated the antispasmodic activity of guggul on ileum of guinea pig...

BACKGROUND AND STUDY AIMS Antispasmodics may improve mucosal visualization during colonoscope withdrawal, potentially improving polyp and adenoma detection. Meta-analysis and case-control studies suggest a 9 % to 13 % relative increase in adenoma and polyp detection. We aimed to assess the impact of hyoscine butylbromide on the expected visualization during colonoscope withdrawal using a CT col...

Dracocephalum kotschyi Boiss. (Labiatae) is a traditional medicine which is believed to have antispasmodic and analgesic activities. The antispasmodic action of D. kotschyi essential oil has been shown in a previous report. The objective of this research was to study antispasmodic activity of hydroalcoholic extract of D. kotschyi on ileum contractions. Hydroalcoholic extract was obtained from a...

OBJECTIVE Several studies have shown the antispasmodic activity of Matricariarecutita without detailing the underlying mechanism(s). The present study was designed to determine whether the antispasmodic mechanisms of M. recutita extract mediated via histaminergic/cholinergic receptors, Ca2+channels, activation of PKA2 and NO release in isolated rabbit jejunum. MATERIALS AND METHODS The concen...

Dracocephalum kotschyi Boiss, a member of Labiatae family, is a native plant to Iran, which has been reported to have immunomodulatory, antihyperlipidemic and antispasmodic activities. The objective of this research was to study the antispasmodic and antidiarrhoeal activities of hydroalcoholic and hexane extracts of D. kotschyi in mice. Furthermore, the antidiarrhoeal and antispasmodic effect o...

o objective: many biological studies have been done to determine the activity of medicinal plants on gastrointestinal function. since acetylcholine is the major transmitter involved in the gastrointestinal motility and there are some evidences regarding the cholinergic modulatory effect of hops extract, in the present study spasmolytic and antispasmodic action of hops(humulus lupulus) on acetyl...