This study evaluated the effect of aging on the adaptation potential of antioxidants and the accumulation of oxidative damage in fast-twitch muscles in response to non-weight-bearing conditions. Adult and old rats were randomized into 4 groups: normal weight bearing, hind-limb unloading for 3, 7, and 14 days. Activities of manganese superoxide dismutase, copper-zinc superoxide dismutase, catala...

The aim of this study was to observe the effect of folate and antioxidants alone on homocysteine levels and oxidative stress markers, and to evaluate whether their co-administration promotes their effects. One hundred patients with hyperhomocysteinemia were randomized into four equal groups, which were then treated with folate, antioxidants or folate plus antioxidants for 2 months; group IV was...

OBJECTIVES The objective of this study is to investigate the antioxidant effects of garlic extract and crude black seeds' consumption on blood oxidant/antioxidant levels in healthy postmenopausal women. METHODS In total, 30 healthy postmenopausal women (mean age = 50.31 ± 4.23 years) participated. They ingested two garlic soft gels per day (each is equivalent to 1000 mg of fresh garlic bulb) ...

Antioxidant treatment has previously been shown to be neuroprotective in experimental bacterial meningitis. To obtain quantitative evidence for oxidative stress in this disease, we measured the major brain antioxidants ascorbate and reduced glutathione, and the lipid peroxidation endproduct malondialdehyde in the cortex of infant rats infected with Streptococcus pneumoniae. Cortical levels of t...

Diabetes induced by streptozotocin (50 mg/kg body wt, i.p.) in the rats substantially increased the plasma glucose and malondialdehyde levels along with corresponding decrease in the antioxidants levels. Supplementation of vitamin E (200 mg/kg body wt., ip) for 5 weeks resulted in non-significant decrease in the blood glucose levels but plasma malondialdehyde levels were reduced to below normal...

INTRODUCTION The depletion of defensive body chemicals called antioxidants may increase the risk of complications from the most common form of diabetes mellitus. This study aims to evaluate blood serum lipid peroxidation product (malondialdehyde), an antioxidant, in non-insulin dependent male and female type 2 diabetic patients. METHODS Blood serum samples were collected from the diabetic pat...

Iron deficiency is the most common deficiency worldwide, with negative effects on work capacity and on motor and mental development of infants, children, and adolescents, particularly in developing countries. Free radicals were generated due to the oxidative damage to the red blood cells and the exact pro-oxidant & antioxidant status in iron deficiency anemia was still ambiguous. Hence we have ...

Cells continuously produce free radicals and reactive oxygen species (ROS) as part of metabolic processes. These free radicals are neutralized by an elaborate antioxidant defense system consisting of enzymes such as catalase, superoxide dismutase, glutathione peroxidase, and numerous non-enzymatic antioxidants, including vitamins A, E and C, glutathione, ubiquinone, and flavonoids. Exercise can...

Objectives: Iron deficiency anemia (IDA) is the most common nutritional among pregnant women in India. can be supplemented orally or intravenously to treat IDA. Intravenous supplementation of iron risky as there more possibility for production free circulation. The role generation radicals and thereby oxidative stress well known. present study tends evaluate antioxidant status intravenous sucro...