نتایج جستجو برای: Antimicrobial peptides

تعداد نتایج: 158971  

Journal: :novelty in biomedicine 0
mehrzad sadredinamin department of microbiology, school of medicine, shahid beheshti university of medical sciences,p. o. box 1985717443, tehran, iran. faramarz mehrnejad department of life science engineering, faculty of newsciences & technologies, university of tehran,p.o. box 14395-1561, tehran, iran. peyman hosseini department of microbiology, qazvin university of medical sciences,p.o.box: 34185-754 qazvin, iran. farahnoosh doustdar 1- department of microbiology, school of medicine, shahid beheshti university of medical sciences,p. o. box 1985717443, tehran, iran.

antimicrobial peptides (amps) are extensive group of molecules that produced by variety tissues of invertebrate, plants, and animal species which play an important role in their immunity response. amps have different classifications such as; biosynthetic machines, biological sources, biological functions, molecular properties, covalent bonding patterns, three dimensional structures, and molecul...

Asghar Taheri Kafrani , Fatemeh Ghanizadeh, Fatemeh Shabani, Fatemeh Zare Bidoki , Hadi Zare-Zardini, Mona Salehvarzi, Robab Sheikhpour, Zahra Sadri,

Application of chemotherapy in cancerous children leads to reduction of immune system efficiency. Therefore, these children are prone to various infectious diseases. The excessive use of antibiotics can bring about antibiotic resistant strains. Hence, it is essential to investigate new therapies for this problem. On the other hand, the emergence of resistance against multiple drugs is a major p...

بیطرف, امیر, زارع زردینی, هادی, طلوعی نیا, بهناز, هاشمی, اعظم,

Introduction: Today, research in the field of antimicrobial peptides is active. Thus, the aim of this study is to purify and determine biochemical properties (especially antimicrobial effect) of new antimicrobial peptides from skin secretions of bufo kavirensis. Methods: This is a descriptive study. The skin secretions of bufo was purified by biochemical manners and antimicrobial effects was ...

Recently, new molecular breeding and genetic engineering approaches have emerged to overcome the limitations of conventional breeding methods in generating disease-resistance transgenic plants. The use of antimicrobial peptides (AMPs) to produce transgenic plants resistant to a wide range of plant pathogens has achieved great success. Among huge number of AMPs, Dermaseptin B1 (DrsB1), an antimi...

Journal: :تحقیقات دامپزشکی 0
احمد عرفان منش جهاد دانشگاهی واحد تهران، دانشگاه تهران، تهران-ایران؛ مرکز تحقیقات قارچ شناسی، دانشکده دامپزشکی دانشگاه تهران، تهران-ایران حجت اله شکری دانشکده دامپزشکی، دانشگاه تخصصی فناوریهای نوین آمل، آمل-ایران جلال حسن مرکز تحقیقات سم شناسی، دانشکده دامپزشکی دانشگاه تهران، تهران-ایران دنیا نیک آیین جهاد دانشگاهی واحد تهران، دانشگاه تهران، تهران-ایران؛ مرکز تحقیقات قارچ شناسی، دانشکده دامپزشکی دانشگاه تهران، تهران-ایران ثریا غریبی جهاد دانشگاهی واحد تهران، دانشگاه تهران، تهران-ایران علیرضا باهنر گروه بهداشت و کنترل مواد غذایی، دانشکده دامپزشکی دانشگاه تهران، تهران-ایران علیرضا خسروی

background: antimicrobial peptides with relative length (2-100 amino acids) and positive charge (pure charge (+9)-(+2)) are amphiphilic that isolated from a wide range of animals. recently, these peptides have been known as a part of innate immune response. nowadays, more than 500 antimicrobial peptides from animals have been reported. objectives: the aim of this study was to evaluate the anti-...

Ismaili, Ahmad, Khademi, Mitra , Nazarian-Firouzabadi, Farhad,

Background and purpose: Rapid emergence of traditional antibiotic-resistant pathogens is one of the most important global challenges in medical sciences. To this end, substitution of current antibiotics with strong antimicrobial peptides could be of great benefit. Materials and methods: In this study, the DNA sequence encoding dermaseptin B1 (DrsB1) antimicrobial peptide derived from Phyllomed...

Introduction: The study of the effects of synthetic peptides with antibacterial properties can provide more effective antibiotics. This study designed, expressed, and investigated the Sushi 3 tetramer peptide. Subsequently, it was compared in terms of changing antibacterial properties with another Sushi3 tetramer peptide the aspartic acid and proline amino acids of which were replaced with glyc...

Journal: :Current drug targets. Infectious disorders 2002
R E W Hancock A Patrzykat

Over the past decade, levels of bacterial resistance to antibiotics have risen dramatically and "superbugs" resistant to most or all available agents have appeared in the clinic. Thus there is a growing need to discover and introduce new drugs. One potential source of novel antibiotics is the cationic antimicrobial peptides, which have been isolated from most living entities as components of th...

2017
Laszlo Otvos

The preclinical in vitro and in vivo benchmark figures of cationic antimicrobial peptides have to be revisited based on the newly discovered alternative modes of action.

Journal: :Antimicrobial agents and chemotherapy 2001
H Yan R E Hancock

A single animal can express several cationic antimicrobial peptides with different sequences and structures. We demonstrate that mammalian peptides from different structural classes frequently show synergy with each other and selectively show synergy with human lysozyme.

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