epilepsy is one of the most common neurological disorders which a physician might come across in his career life. on the other hand, migraine is common disorders in society chronic headache such as migraine in epileptic patients give ride to difficulties in seizure treatment due to altering the sleeping pattern and calmness disarrangement. therefore, early diagnosis and suitable treatment in ep...

mothers exposed to antiepileptic drugs (aeds) are at high risk to born babies with orofacial malformations such as cleft lips. about 9 percent of congenital abnormalities in babies of mothers with epilepsy relates to orofacial abnormalities. maintaining safe antiepileptic drugs for millions of mothers with epilepsy is very important. researches show that new aeds have less side effects than the...

how to cite this article: karimzadeh p, ashrafi mr, bakhshandeh bali mk, nasehi mm, taheri otaghsara sm, taghdiri mm, ghofrani m. zonisamide efficacy as adjunctive therapy in children with refractory epilepsy. iran j child neurol. 2013 spring; 7(2):37-42. objective approximately one third of epileptic children do not achieve complete seizure improvement. zonisamide is a new antiepileptic drug w...

background: the challenge of antiepileptic drugs (aeds) management is to attain the best compromise between the desire to maximize seizure control and the need to keep side‑effects within tolerable limits for the individual patient. to reduce devastation in iranian epileptic patients, the aim of this study was to explore the overall outcome following aeds prescription. methods: a cross‑sectiona...

how to cite this article: karimzadeh p, bakrani v. antiepileptic drug-related adverse reactions and factors influencing these reactions. iran j child neurol. 2013 summer; 7(3):23-27.   objective according to the basic role of drug side effects in selection of an appropriate drug, patient compliance and the quality of life in epileptic patients, and forasmuch as new dugs with unknown side effect...

the new-aeds, whose developments were motivated following the discovery of the valproate and its marketing in the u.s in 1978, have presented more therapeutic options. there are approximately twenty four fda-approved antiepileptic drugs for use in patients with epilepsy, five of which were identified and have come on to the market between 2009 and 2012. the new-aeds are of interest, not due to ...

background: diminished libido and sexual dysfunction are unusually common among male epileptic patients. the most important etiologic factor may be antiepileptic drugs (aeds)-induced androgen deficiency. we compared reproductive hormone levels among men with epilepsy taking various aeds and normal controls. methods: subjects were 59 male epileptic patients who aged 24 ± 5 years. they had been r...

objective(s): anti-epileptic drugs (aeds) have the potential to affect fetal development throughout pregnancy. considering the broad therapeutic indications of pregabalin (pgb), its potential teratogenic effects and the levels of homocysteine have been studied.   materials and methods: timed-pregnant mice received one of three doses of pgb (20, 40 or 80 mg/kg/day) or the vehicle control during ...

background: valproic acid (vpa) is an effective antiepileptic drug widely used worldwide. despite several studies indicating the usefulness of intravenous l-carnitine in the treatment of vpa poisoning, this drug is not readily available in iran. the aim of this study was to determine whether supportive care without antidote would result in acceptable outcomes in vpa poisoned patients. materials...