Coprinol, a new antibacterial cuparane, was isolated from fermentations of a Coprinus sp. Its biological activities were investigated and its structure was elucidated by spectroscopic methods. The new antibiotic exhibited activitiy against multidrug-resistant Gram-positive bacteria in vitro. Two derivatives were synthesized and their activities compared to the parent compound.

3-Bromo acetyl coumarins (4a-c) on treatment with methyl and ethyl esters of nicotinic acid, isonicotinic acid (5a-d) gave 3-coumrinoyl pyridinium bromides (7a-l) and with quinoline (6) gave 3-coumarinoyl quinolinium bromides (8a-c). The structures of the final compounds were established by their spectral data. The antimicrobial activitiy of all the newly synthesized test compounds were evaluat...

ABSTRACT. Polyaniline-tin(IV)molybdophosphate composite exchanger was prepared using sol–gel method by mixing polyaniline gel into the inorganic precipitates of tin(IV)molybdophosphate. The ion characterized various techniques such as XRD, UV-Vis, FTIR, SEM-EDX, and PL. Photocatalytic activities antibacterial efficiencies bare polymer (PANI), tin(IV)molybdophosphate (TMP) polyaniline-tin(IV)mol...

Flavonoids are a heterogeneous group of polyphenolic compounds found ubiquitously in a wide variety of plants. Their chemical structure is based on 2-phenyl chromen, also known as flavan [1]. Flavonoids display a wide range of pharmacological properties, including antiinflammatory, antioxidative, antiviral, antibacterial and antiproliferative activities [1, 2]. Previous studies carried out by o...

Introduction: Gardnerella vaginalis is a significant pathogen associated more frequently with genital and rarely extragenital infections in women of reproductive age. Few natural antimicrobial agents such as soap nut, garlic, calendula oil are reported to inhibit the growth of G.vaginalis. The present study was intended to investigate the antibacterial and antibiofilm actions of Tea Tree oil an...

Essential components of the aerial parts of Œnante virgata have been studied by gas chromatography-mass spectrometry to afford 27 component, the major components were found to be, Citral (41.71%), α-Bisabolol (21.81%) Dihydrocarviol acetate (11.37%). The antimicrobial activitiy of the essential oils were evaluated by disc diffusion method and tested against Gram-negative Escherichia coli, Staph...

In recent years, the availability and use of various antibiotics and antimicrobial agents have resulted in increase of drug resistant pathogens. Therefore, scientist’s attention has been diverted to find a suitable replacement for antimicrobial treatment. Graphene (G), as a two-dimensional (2D) carbon-based nanomaterials (CBNs) has a unique physicochemical properties including thermal, optical ...

Essential oils (EOs) with a wide spectrum of antibacterial activities have been suggested as potent alternative sources for controlling multidrug-resistant bacteria. This paper presented the evaluation anti-H. pylori activity EOs from rhizomes Zingiber officinale, Curcuma zedoaria, longa and Alpinia officinarum. The Eos, obtained by steam distillation method, were evaluated their minimal inhibi...

Several diaza-analogs of phenanthrene derived from 3-amino, 5-amino, 6-amino, 8-aminoquinolines, and 5-aminoisoquinoline were prepared to evaluate their antiplasmodial activities. All compounds showed mild to good activitiy in vitro, both on a Nigerian chloroquino-sensitive strain and on the chloroquino-resistant FcB1-Columbia and FcM29 strains. The position of the intracyclic nitrogen atom is ...