the purpose of this research was to formulate and systemically evaluate in-vitro and in-vivo performances of mucoadhesive propranolol hydrochloride microspheres for its potential use in the treatment of hypertension, myocardial infraction and cardiac arrhythmias. propranolol hydrochloride mucoadhesive microspheres, containing carbopol-934p as mucoadhesive polymer and ethyl cellulose as carrier ...

cosmos caudatus is widely used as a traditional medicine in southeast asia. c. caudatus has been reported as a rich source of bioactive  compounds such as ascorbic acid, quercetin, and chlorogenic acid. studies have shown that c. caudatus exhibits high antioxidant capacity and various medicinal properties, including anti-diabetic activity, anti-hypertensive properties, anti-infl ammatory respon...

lisinopril dihydrate (angiotensin converting enzyme inhibitor) is a lysine derivative of enalaprilat and does not require hydrolysis to exert pharmacological activity. it has an extensive hepatic first pass metabolism resulting in a bioavailabil-ity of 6-60%. to overcome the poor bioavailability of the drug, transdermal patches have been prepared. the present study also aims at optimization of ...

r 200 001 : +972 5 ileh@na Summary Background and objective: Anti-hypertensive medications are recommended for prevention of recurrent ischemic stroke in hypertensive and normotensive patients. The objective of this study was to analyze the use of anti-hypertensive therapy in acute ischemic stroke survivors. Methods: All ischemic stroke survivors discharged from Al-watani governmental hospital ...

BACKGROUND It has been suggested that anti-hypertensive medications may worsen leg ischemia in peripheral artery disease (PAD) patients. We undertook a meta-analysis to assess the effect of anti-hypertensive medications on measures of leg ischemia including maximum walking distance (MWD), pain free walking distance (PFWD) and ankle brachial pressure index (ABPI). A meta-regression was performed...

Several therapeutic effects including diuretic, anti-pyretic and anti-scurvy have been reported for Portulaca oleracea. In previous studies the analgesic, anti-inflammatory, anti-hypertensive, anti-oxidant, muscle relaxant effects and neuropharmacological effects of the aqueous extract of Portulaca oleracea have been demonstrated on experimental animals. In the present study the antitussive eff...

Several therapeutic effects including diuretic, anti-pyretic and anti-scurvy have been reported for Portulaca oleracea. In previous studies the analgesic, anti-inflammatory, anti-hypertensive, anti-oxidant, muscle relaxant effects and neuropharmacological effects of the aqueous extract of Portulaca oleracea have been demonstrated on experimental animals. In the present study the antitussive eff...

1. In this study an acute anti-hypertensive effect of three anti-oxidant agents (vitamin C, thiopronine and glutathione) in hypertensive subjects and in both hypertensive and non-hypertensive diabetic patients is reported. 2. The anti-oxidants had no effect on blood pressure in healthy normal subjects at a dose of 6 mmol, but thiopronine and glutathione produced a significant hypotensive effect...

purpose : to investigate the association of primary open angle glaucoma (poag) and systemic hypertension in patients referred to farabi eye hospital methods : in this case-control study in farabi eye hospital. one hundred patients were selected randomly from poag patients of glaucoma clinic, farabi eye hospital. control group consists of 100 patients, candidates for cataract surgery. history of...

Quinoa (Chenopodium quinoa), sorghum (Sorghum bicolor) and flaxseed (Linum usitassimum L.) are grains seeds popularly known for their nutritional values. This review aimed to discuss the profile of these seeds, bioactive compounds how those help prevent chronic diseases. These crops were selected this study as they all free gluten; a rich source protein, have low glycemic index (GI) i.e. do not...