نتایج جستجو برای: Anti-alzheimer

تعداد نتایج: 376071  

Journal: :iranian journal of pharmaceutical sciences 0
alama badrul department of pharmacy, atish dipankar university of science and technology, dhaka, bangladesh haque ekramul department of pharmacy, brac university, dhaka, bangladesh

the crude methanolic extract of the seeds of celastrus paniculatus along with its organic soluble fractions were tested for their possible antioxidant and anti-alzheirmer (ad) activity. the extracts showed prominent dpph free radical scavenging activity, inhibiting activity of authentic peroxynitrite (onoo-) and inhibition of total reactive oxygen species (ros) generation. in dpph radical scave...

B Asghari, M Ghorbani Nohooji,

Background: Thymus persicus is one of the Iranian endemic medicinal plants, that its decoction and various products have plenty of food and pharmaceutical uses. Objective: Evaluation of T. persicus products metabolite contains and determination of the best antioxidant, anti-diabetic and anti-Alzheimer extract. Methods: Samples total phenolic, flavonoid and tannin contents were determined by F...

Journal: :iranian journal of basic medical sciences 0
ali mohammadi karakani institute of biochemistry and biophysics, university of tehran, tehran, iran gholamhossein riazi institute of biochemistry and biophysics, university of tehran, tehran, iran seyed mahmood ghaffari institute of biochemistry and biophysics, university of tehran, tehran, iran shahin ahmadian institute of biochemistry and biophysics, university of tehran, tehran, iran farzad mokhtari institute of biochemistry and biophysics, university of tehran, tehran, iran mahshad jalili firuzi institute of biochemistry and biophysics, university of tehran, tehran, iran

objective(s):alzheimer's disease (ad) is the most common age-related neurodegenerative disorder. one of the hallmarks of ad is an abnormal accumulation of fibril forms of tau protein which is known as a microtubule associated protein. in this regard, inhibition of tau aggregation has been documented to be a potent therapeutic approach in ad and tauopathies. unfortunately, the available syn...

Journal: :international journal of preventive medicine 0
rokhsareh meamar gholamreza askari majid ghasemi mohammad reza aghaye ghazvini sahar vesal mostafa sharifkhah

background: alzheimer’s disease (ad) is one of the most important neurodegenerative disorder. anti‑cyclic citrullinated peptide (anti‑ccp) may all be involved in the development of vascular disease such as ad. the aim of this study is detection of seropositivity for anti‑ccp antibody in ad patients. methods: in our study, 30 patients with ad and 29 healthy controls (age and‑sex matched) were re...

Journal: :مجله علوم اعصاب شفای خاتم 0
ali ebrahimi a. islamic azad university, mashhad branch, mashhad, iran b. members of mashhad neuroscience research group of islamic azad university, mashhad branch, mashhad, iran anahita ghazaghi a. islamic azad university, mashhad branch, mashhad, iran b. members of mashhad neuroscience research group of islamic azad university, mashhad branch, mashhad, iran malihe bahadoran a. islamic azad university, mashhad branch, mashhad, iran b. members of mashhad neuroscience research group of islamic azad university, mashhad branch, mashhad, iran faramarz khojaste a. islamic azad university, mashhad branch, mashhad, iran b. members of mashhad neuroscience research group of islamic azad university, mashhad branch, mashhad, iran

alzheimer's disease (ad) is a chronic neurodegenerative disease that accounts for 60 to 80 percent of all dementia cases. the exact cause of alzheimer`s disease is still unknown, but recent studies suggest neuro-inflammation as an important part of the pathogenesis of the disease. this brings in mind using non-steroidal anti-inflammatory drugs (nsaid) as treatment or prevention of the dise...

Journal: :Archives of neurology 2000
G M Halliday C E Shepherd H McCann W G Reid D A Grayson G A Broe J J Kril

BACKGROUND There has been no analysis of brain tissue from longitudinally observed, cognitively tested patients to validate whether anti-inflammatory medications protect against the pathological changes of Alzheimer disease. OBJECTIVE To investigate the role of anti-inflammatory medications in alleviating the pathological features of Alzheimer disease. DESIGN AND MAIN OUTCOME MEASURES A 5-y...

Ali Ebrahimi, Anahita Ghazaghi, Faramarz Khojaste, Malihe Bahadoran,

Alzheimer's disease (AD) is a chronic neurodegenerative disease that accounts for 60 to 80 percent of all dementia cases. The exact cause of Alzheimer`s disease is still unknown, but recent studies suggest neuro-inflammation as an important part of the pathogenesis of the disease. This brings in mind using non-steroidal anti-inflammatory drugs (NSAID) as treatment or prevention of the disease. ...

Journal: :Hacettepe University Journal of the Faculty of Pharmacy 2023

Demansın en yaygın şekli olan Alzheimer hastalığı, hafıza kaybı ve diğer bilişsel problemler ile karakterize karmaşık bir hastalıktır. Artan prevalansa sahip hastalığının fizyopatolojisinin anlaşılması bu hastalığın tedavisinde etkin bileşiklerin yapılarının araştırılması, yeni ilaç moleküllerinin geliştirilmesine yardımcı olacaktır. Bu anlamda hastalık üzerinde etkili hipotezlerin, yapısının e...

Journal: :Brain communications 2023

This scientific commentary refers to “Key questions for the evaluation of anti-amyloid immunotherapies Alzheimer”s disease', by Liu et al. (https://doi.org/10.1093/braincomms/fcad175)

Background and Objectives: Alzheimer’s disease (AD) is a neurodegenerative disease accompanied by common emotional symptoms such as anxiety and fear. The aim of this study was investigating the anti-anxiety and antioxidant effects of sumac extract and its nano-phytosome, in streptozotocin (STZ)-induced rat model of Alzheimerchr('39')s disease Materials and Methods: In this experimental study, ...

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