نتایج جستجو برای: Anti-Sense Oligonucleotides
تعداد نتایج: 520090 فیلتر نتایج به سال:
In the present study, using anti-sense oligonucleotides the inhibition of expression of the PML protein hasbeen investigated. The anti-sense oligonucleotides were designed against the translation initiation site ofthe PML gene, and their effects were investigated on cellular growth and DNA synthesis. Incubation of normalhuman fibroblast cells with the anti-sense oligonucleotid...
background: dendritic cells (dcs) are ideal accessory cells in the field of gene therapy. delivery of dna and sirna into mammalian cells is a useful technique in treating various diseases caused by single gene defects. selective gene silencing by small interfering rnas (sirnas) and antisense oligodeoxynucleotides (odn)s is an efficient method for the manipulation of cellular functions. an effic...
Prediction of microRNA-mRNA interaction typically relies on bioinformatic methods, but these methods only suggest the possibility of microRNA binding and may miss important interactions as well as falsely predict others. A major obstacle to the miRNA research has been the lack of experimental procedures for the identification of miRNA-mRNA interactions. Recently, a few studies have attempted to...
Background: Dendritic cells (DCs) are ideal accessory cells in the field of gene therapy. Delivery of DNA and siRNA into mammalian cells is a useful technique in treating various diseases caused by single gene defects. Selective gene silencing by small interfering RNAs (siRNAs) and antisense oligodeoxynucleotides (ODN)s is an efficient method for the manipulation of cellular functions. An effic...
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