epilepsy is one of the most common chronic disorders affecting individuals of all ages. a greater understanding of pathogenesis in epilepsy will likely provide the basis fundamental for development of new antiepileptic therapies that aim to prevent the epileptogenesis process or modify the progression of epilepsy in addition to treatment of epilepsy symptomatically. therefore, several investiga...

We summarize some of the most frequenthly used rodent animal models of temporal lobe epileps and the impact of chemoconvulsants on them. Temporal lobe epilepsy is the most common epilepsy in humans in which seizures spread to the neighboring cortiase and hippocampal neuron loss and other neuropathological take place. Temporal lobe epilepsy and the other form of epilepsy cannot acquired in chini...

  Epilepsy is one of the most common chronic disorders affecting individuals of all ages. A greater understanding of pathogenesis in epilepsy will likely provide the basis fundamental for development of new antiepileptic therapies that aim to prevent the epileptogenesis process or modify the progression of epilepsy in addition to treatment of epilepsy symptomatically. Therefore, severa...

abstract aim and background: evaluation of cognition is fundamental for every comprehensive epilepsy program. we sought to conduct this study to assess memory state of patients with refractory temporal lobe epilepsy before decision for epilepsy surgery. method and materials: in a case-control study, 20 patients with right temporal lobe epilepsy and 20 patients with left temporal lobe epilepsy w...

Background: Epilepsy is considered as one of the most important disorders in neurology. Temporal lobe epilepsy is a form of epilepsy including two main types of mesial and lateral (neocortex). Objectives: Determination and comparison of electroencephalogram (EEG) pattern in the ictal and interictal phases of mesial and lateral temporal lobe epilepsy. Materials and Methods: This cross-sectiona...

background and aim: electrical discharges in temporal lobe epilepsy can cause disorders in auditory pathways. staggered spondaic word test ( ssw) is one of the most common behavioral tests to evaluate the central auditory nervous system. this study aimed to evaluate and compare auditory processing problems in temporal lobe epileptic patients and normal subjects with persian ssw test. methods: t...

anxiety and depression are very common in population and occur in a wide range of clinical states and is very common in epileptic patients. many recent epidemiological studies have found a high prevalence of depression and anxiety in epileptic patients. these studies found that epileptic patients suffered from depression and anxiety than those without epilepsy. the prevalence of depression or a...

epilepsy as one of the most common neurological disorders affects more than 50 million people worldwide with a higher prevalence rate in low-income countries. excessive electrical discharges in neurons following neural cell damage or loss cause recurrent seizures. one of the most common and difficult to treat types of epilepsy is temporal lobe epilepsy (tle) which results from hippocampal scler...

Epilepsy is the third most common chronic brain disorder which is characterized by an enduring predisposition to generate seizures. Mesial Temporal Lobe Epilepsy (MTLE) is the most common type of refractory epilepsy. Increasing evidence indicates that neuroinflammation plays a critical role in the pathogenesis of MTLE. Hundreds of micro-RNAs have been found to be abnormally expressed in epilept...

epilepsy is the third most common chronic brain disorder which is characterized by an enduring predisposition to generate seizures. mesial temporal lobe epilepsy (mtle) is the most common type of refractory epilepsy. increasing evidence indicates that neuroinflammation plays a critical role in the pathogenesis of mtle. hundreds of micro-rnas have been found to be abnormally expressed in epilept...