this paper intends to compare the abilities of the two major imaging modalities in nuclear medicine imaging: positron emission tomography (pet) and single photon emission computed tomography (spect). the motivations are many-fold: (i) to gain a better understanding of the strengths and limitations of the two imaging modalities in the context of recent and ongoing developments in hardware and so...

Positron emission tomography (PET) is well established as an important research and clinical molecular imaging modality. Although the size differences between humans and rodents create formidable challenges for the application of PET imaging in small animals, advances in technology over the past several years have enabled the translation of this imaging modality to preclinical applications. In ...

Animal models can be used in the study of disease. This chapter discusses imaging animal models to elucidate the process of human disease. The mouse is used as the primary model. Though this choice simplifies many research choices, it necessitates compromises for in vivo imaging. In the future, we can expect improvements in both animal models and imaging techniques.

introduction: gallium-67 citrate has been known as a good infection agent in nuclear medicine for decades. in this work the value of 67ga-citrate has been investigated in infected animal models using spect imaging at optimized/standardized conditions. methods: the bacterial (staphylococcus aureus; s.a. and escherichia coli; e.c.) and fungal (candidae albicans; c.a.) species from standard sourc...