introduction: in patients with uncomplicated primary hypertension (htn), angiotensin converting enzyme inhibitors (aceis) are considered as monotherapy. in some studies, cough was not related to age, sex, underlying disease, or drug dosage. however, in previous studies, the incidence of cough was greater in females than males. the aim of this study is to determine the incidence of captopril-ind...

background: central renin angiotensin system has an important role on the cerebral microcirculation and metabolism. our previous work showed that inhibition of angiotensin converting enzyme (ace) activity prior to induction of ischemia protected the brain from severe ischemia/reperfusion (i/r) injuries. this study evaluated the impacts of post-ischemic inhibition of ace, enalapril, on brain inf...

conclusions traditional medicine based on certain plants could be of beneficial effects in hypertension treatment. results in total, 52 species out of the 135 (39%) screened, gave more than 50% ace inhibition. forty species were found to possess a high ace inhibiting ability and were low in their tannin content. materials and methods in the present study 135 plants used in traditional persian m...

background: early diagnosis of albuminuria and the prevention of its progression to macroalbuminuria and diabetic nephropathy are crucial. angiotensin converting enzyme inhibitors (aceis) and antagonists of angiotensin ii receptors type i (arbs) are currently used as first-line treatment for albuminuria in these patients. the present study was conducted to assess the efficacy of addition of spi...

background: renal ischemia reperfusion (ir) injury has been a major source of concern during the past decades and angiotensin converting enzyme (ace) inhibitors have been successfully used to prevent this injury. there have been some controversial reports about the involvement of katp channels in the mechanism of action of ace inhibitors. in this study, we examined the effect of katp channel bl...

background: there is controversy over the potential benefits/harms of the usage of angiotensin-converting enzyme inhibitors (aceis) or angiotensin receptor blockers (arbs) as regards the postoperative mortality of coronary artery bypass grafting (cabg). this study investigates the correlation between the in-hospital mortality of cabg and the preoperative administration of acei/arb. methods: out...

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Background and aims: Diabetic nephropathy (DN) is the most common cause of end-stage renal failure which could increase the risk of cardiovascular disease and morbidity and mortality in patients. The aim of this study was to investigate new modalities for treatment of diabetic nephropathy. Methods:This study was a mini-review research to investigate drugs that are used for DN treatment. Resul...